The alternative matrisome: alternative splicing of ECM proteins in development, homeostasis and tumor progression

Z Rekad, V Izzi, R Lamba, D Ciais… - Matrix Biology, 2022 - Elsevier
The extracellular matrix (ECM) is a fundamental component of the tissue of multicellular
organisms that is comprised of an intricate network of multidomain proteins and associated …

Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly

J Jacobson, LLY Chu, S Ramu - US Patent 10,207,240, 2019 - Google Patents
US10207240B2 - Methods and microfluidic devices for the manipulation of droplets in high
fidelity polynucleotide assembly - Google Patents US10207240B2 - Methods and microfluidic …

Methods for sorting nucleic acids and multiplexed preparative in vitro cloning

J Jacobson, MJ Goldberg, AK Li-yun… - US Patent …, 2018 - Google Patents
Methods and compositions relate to the sorting and cloning of high fidelity nucleic acids
using high throughput sequencing. Specifically, nucleic acid molecules having the desired …

Protein arrays and methods of using and making the same

J Jacobson, ME Hudson, LLY Chu - US Patent 10,457,935, 2019 - Google Patents
Methods and devices are provided for preparing a protein array having a plurality of
proteins. In one embodiment, the method includes providing a plurality of nucleic acids each …

Microarray synthesis and assembly of gene-length polynucleotides

AV Oleinikov - US Patent 8,058,004, 2011 - Google Patents
There is disclosed a process for in vitro synthesis and assembly of long, gene-length
polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in …

Microfluidic devices and methods for gene synthesis

LLY Chu - US Patent 9,216,414, 2015 - Google Patents
US9216414B2 - Microfluidic devices and methods for gene synthesis - Google Patents
US9216414B2 - Microfluidic devices and methods for gene synthesis - Google Patents …

Identification and characterization of alternative exon usage linked glioblastoma multiforme survival

A Sadeque, NVL Serão, BR Southey, KR Delfino… - BMC medical …, 2012 - Springer
Background Alternative exon usage (AEU) is an important component of gene regulation.
Exon expression platforms allow the detection of associations between AEU and …

Microarray synthesis and assembly of gene-length polynucleotides

AV Oleinikov - US Patent 10,450,560, 2019 - Google Patents
There is disclosed a process for in vitro synthesis and assembly of long, gene-length
polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in …

Assembly of high fidelity polynucleotides

J Jacobson, LLY Chu - US Patent 9,217,144, 2015 - Google Patents
(60) Provisional application No. 61/293,192, filed on Jan. Microarray Bioinformatics', Nat.
Genet. S21: 10; Cambridge Uni 7, 2010, provisional application No. 61/310,076, filed versity …

Microarray synthesis and assembly of gene-length polynucleotides

AV Oleinikov - US Patent 9,051,666, 2015 - Google Patents
There is disclosed a process for in vitro synthesis and assem bly of long, gene-length
polynucleotides based upon assem bly of multiple shorter oligonucleotides synthesized in …