Defeating Alzheimer's disease and other dementias: a priority for European science and society

B Winblad, P Amouyel, S Andrieu, C Ballard… - The Lancet …, 2016 - thelancet.com
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

Cognitive symptoms of Alzheimer's disease: clinical management and prevention

E Joe, JM Ringman - bmj, 2019 - bmj.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
accumulation of amyloid β in the form of extracellular plaques and by intracellular …

The clinical promise of biomarkers of synapse damage or loss in Alzheimer's disease

M Colom-Cadena, T Spires-Jones, H Zetterberg… - Alzheimer's research & …, 2020 - Springer
Background Synapse damage and loss are fundamental to the pathophysiology of
Alzheimer's disease (AD) and lead to reduced cognitive function. The goal of this review is to …

Very long-chain n-3 fatty acids and human health: fact, fiction and the future

PC Calder - Proceedings of the Nutrition Society, 2018 - cambridge.org
EPA and DHA appear to be the most important n-3 fatty acids, but roles for n-3
docosapentaenoic acid are now also emerging. Intakes of EPA and DHA are usually low …

Docosahexaenoic acid and cognition throughout the lifespan

MJ Weiser, CM Butt, MH Mohajeri - Nutrients, 2016 - mdpi.com
Docosahexaenoic acid (DHA) is the predominant omega-3 (n-3) polyunsaturated fatty acid
(PUFA) found in the brain and can affect neurological function by modulating signal …

Omega-3 fatty acids and neurodegenerative diseases: new evidence in clinical trials

R Avallone, G Vitale, M Bertolotti - International journal of molecular …, 2019 - mdpi.com
A nutritional approach could be a promising strategy to prevent or slow the progression of
neurodegenerative diseases such as Parkinson's and Alzheimer's disease, since there is no …

Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration

CIF Janssen, AJ Kiliaan - Progress in lipid research, 2014 - Elsevier
Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated
fatty acids (LCPUFA) in neural development and neurodegeneration. This review will focus …

Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies

F Pistollato, RC Iglesias, R Ruiz, S Aparicio… - Pharmacological …, 2018 - Elsevier
Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors
and the onset and consolidation of dementia and Alzheimer's disease (AD). It has been …

36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease

H Soininen, A Solomon, PJ Visser… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction The LipiDiDiet trial investigates the effects of the specific multinutrient
combination Fortasyn Connect on cognition and related measures in prodromal Alzheimer's …

Alzheimer's disease

CL Masters, R Bateman, K Blennow… - Nature reviews disease …, 2015 - nature.com
Alzheimer's disease is a chronic illness with long preclinical and prodromal phases (20
years) and an average clinical duration of 8–10 years. The disease has an estimated …