Potassium ion channels in glioma: From basic knowledge into therapeutic applications
Ion channels, specifically those controlling the flux of potassium across cell membranes,
have recently been shown to exhibit an important role in the pathophysiology of glioma, the …
have recently been shown to exhibit an important role in the pathophysiology of glioma, the …
Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis
P Pukkanasut, R Jaskula-Sztul, JC Gomora… - Frontiers in …, 2024 - frontiersin.org
This review focuses on the expression and function of voltage-gated sodium channel
subtype NaV1. 7 in various cancers and explores its impact on the metastasis driving cell …
subtype NaV1. 7 in various cancers and explores its impact on the metastasis driving cell …
Voltage-Gated Sodium Channel NaV1.7 Inhibitors with Potent Anticancer Activities in Medullary Thyroid Cancer Cells
P Pukkanasut, J Whitt, R Guenter, SE Lynch… - Cancers, 2023 - mdpi.com
Simple Summary Despite the recent advances in the diagnosis and treatment of medullary
thyroid cancer (MTC), it remains an understudied cancer type and continues to …
thyroid cancer (MTC), it remains an understudied cancer type and continues to …
NaII-Pred: An ensemble-learning framework for the identification and interpretation of sodium ion inhibitors by fusing multiple feature representation
High-affinity ligand peptides for ion channels are essential for controlling the flow of ions
across the plasma membrane. These peptides are now being investigated as possible …
across the plasma membrane. These peptides are now being investigated as possible …
Malignant currents: sodium leak channel NALCN propels prostate cancer aggressiveness
I Stejerean‐Todoran, I Bogeski - The EMBO Journal, 2023 - embopress.org
Although ion transporters and channels have been extensively studied over the last couple
of decades, there are still unresolved aspects with regards to their contribution to cancer cell …
of decades, there are still unresolved aspects with regards to their contribution to cancer cell …
SOX11 as a prognostic biomarker linked to m6A modification and immune infiltration in renal clear cell carcinoma
K Wang, X Chen, Y Liu, X Meng… - Translational Cancer …, 2024 - pmc.ncbi.nlm.nih.gov
Background The prognosis for patients with kidney renal clear cell carcinoma (KIRC)
remains unfavorable, and the understanding of SRY-box transcription factor 11 (SOX11) in …
remains unfavorable, and the understanding of SRY-box transcription factor 11 (SOX11) in …
[HTML][HTML] Distinct Host Gene Targets and Mode of Action in the MicroRNA of Nipah Virus from Malaysia and Bangladesh: A Comparative in-silico Based Analysis
Background: Since the emergence of the Nipah virus in Malaysia in 1998, two major variants
of the virus, Nipah Virus Malaysian (NiV-M) and NiV Bangladesh (NiV-B) have been …
of the virus, Nipah Virus Malaysian (NiV-M) and NiV Bangladesh (NiV-B) have been …
Cardiac Cross-Reactivity of NaV Autoantibodies in Metastatic Breast Cancer: A Possible Trigger for Sudden Cardiac Death
C Pappone, A Tarantino, D Melgari, M Piccoli… - medRxiv, 2024 - medrxiv.org
Background and Aims Patients with metastatic breast cancer have an increased risk of
sudden cardiac death (SCD) that cannot be fully explained by cardiotoxic treatments. Recent …
sudden cardiac death (SCD) that cannot be fully explained by cardiotoxic treatments. Recent …
Ion transporting proteins and cancer: Progress and perspectives
MBA Djamgoz - Targets of Cancer Diagnosis and Treatment: Ion …, 2022 - Springer
Ion transporting proteins (ITPs) comprise a wide range of ion channels, exchangers, pumps
and ionotropic receptors many of which are expressed in tumours and contribute …
and ionotropic receptors many of which are expressed in tumours and contribute …
Análisis de expresión diferencial de genes codificantes para canales de sodio dependientes de voltaje en subtipos histológicos de cáncer cervical
AL Cortés Loaiza - 2024 - repositorio.ucaldas.edu.co
Cervical cancer (CaC) ranks fourth in incidence and mortality in the female population
worldwide. This type of cancer is histologically classified according to the region of the cervix …
worldwide. This type of cancer is histologically classified according to the region of the cervix …