Recent advances in targeted nanomedicine as promising antitumor therapeutics

S Hejmady, R Pradhan, A Alexander, M Agrawal… - Drug discovery today, 2020 - Elsevier
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …

The Dual Role of the Liver in Nanomedicine as an Actor in the Elimination of Nanostructures or a Therapeutic Target

L Baboci, S Capolla, F Di Cintio, F Colombo… - Journal of …, 2020 - Wiley Online Library
The development of nanostructures for therapeutic purpose is rapidly growing, following the
results obtained in vivo in animal models and in the clinical trials. Unfortunately, the potential …

Apigenin loaded nanoparticle delayed development of hepatocellular carcinoma in rats

S Bhattacharya, L Mondal, B Mukherjee, L Dutta… - … , Biology and Medicine, 2018 - Elsevier
Hepatocellular carcinoma (HCC) is one of the major causes of cancer related death globally.
Apigenin, a dietary flavonoid, possesses anti-tumor activity against HCC cells in-vitro …

Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft

J Kazi, R Sen, S Ganguly, T Jha, S Ganguly… - International Journal of …, 2020 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green tea
exhibits significant anti-cancer potential over a wide range of cancer cells. We have …

Aptamer-functionalized drug nanocarrier improves hepatocellular carcinoma toward normal by targeting neoplastic hepatocytes

S Chakraborty, ZY Dlie, S Chakraborty, S Roy… - … Therapy-Nucleic Acids, 2020 - cell.com
Site-specific delivery of chemotherapeutics specifically to neoplastic hepatocytes without
affecting normal hepatocytes should be a focus for potential therapeutic management of …

Electrospinning of linezolid loaded PLGA nanofibers: effect of solvents on its spinnability, drug delivery, mechanical properties, and antibacterial activities

T Eren Boncu, N Ozdemir… - Drug development and …, 2020 - Taylor & Francis
Objective: The choice of a desirable solvent/solvent system is fundamental for optimization
of electrospinning by altering the rheological and electrostatic properties of the polymer …

Redox-degradable microgel based on poly (acrylic acid) as drug-carrier with very high drug-loading capacity and decreased toxicity against healthy cells

M Mackiewicz, S Dagdelen, K Marcisz… - Polymer Degradation …, 2021 - Elsevier
In this paper we report on synthesis of pH sensitive and degradable microgel for a high-
capacity doxorubicin-drug carrier. Microgel was based on poly (acrylic acid) cross-linked …

Cetuximab-conjugated PLGA nanoparticles as a prospective targeting therapeutics for non-small cell lung cancer

L Kumari, I Ehsan, A Mondal, A Al Hoque… - Journal of Drug …, 2023 - Taylor & Francis
Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers diagnosed
worldwide, yet managing it is still challenging. The epidermal growth factor receptor (EGFR) …

Anticancer potential of docetaxel-loaded cobalt ferrite nanocarrier: an in vitro study on MCF-7 and MDA-MB-231 cell lines

J Panda, BS Satapathy, B Mandal, R Sen… - Journal of …, 2021 - Taylor & Francis
Aim To develop a biocompatible cobalt ferrite (CF-NP) nanodrug formulation using oleic
acid and poly (d, l-lactide-co-glycolic) acid (PLGA) for the delivery of docetaxel (DTX) …

Synthesis and bioconjugation of hybrid nanostructures for biomedical applications

AP Tiwari, SS Rohiwal - Hybrid nanostructures for cancer theranostics, 2019 - Elsevier
In recent years, nanostructures have come to represent a new class of materials which have
been explored for healthcare-related applications. These nanohybrids are important for their …