Microbial production of advanced biofuels

J Keasling, H Garcia Martin, TS Lee… - Nature Reviews …, 2021 - nature.com
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021 - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

What can ribo-seq, immunopeptidomics, and proteomics tell us about the noncanonical proteome?

JR Prensner, JG Abelin, LW Kok, KR Clauser… - Molecular & Cellular …, 2023 - ASBMB
Abstract Ribosome profiling (Ribo-Seq) has proven transformative for our understanding of
the human genome and proteome by illuminating thousands of noncanonical sites of …

Recent advances in machine learning applications in metabolic engineering

P Patra, BR Disha, P Kundu, M Das, A Ghosh - Biotechnology Advances, 2023 - Elsevier
Metabolic engineering encompasses several widely-used strategies, which currently hold a
high seat in the field of biotechnology when its potential is manifesting through a plethora of …

Machine learning applications in systems metabolic engineering

GB Kim, WJ Kim, HU Kim, SY Lee - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Application of machine learning in biotechnology is becoming essential.•Machine
learning is increasingly applied to advance systems metabolic engineering.•Machine …

Uncovering the small proteome of Methanosarcina mazei using Ribo-seq and peptidomics under different nitrogen conditions

MA Tufail, B Jordan, L Hadjeras, R Gelhausen… - Nature …, 2024 - nature.com
The mesophilic methanogenic archaeal model organism Methanosarcina mazei strain Gö1
is crucial for climate and environmental research due to its ability to produce methane. Here …

[HTML][HTML] Thousands of small, novel genes predicted in global phage genomes

BJ Fremin, AS Bhatt, NC Kyrpides, A Sengupta… - Cell reports, 2022 - cell.com
Summary Small genes (< 150 nucleotides) have been systematically overlooked in phage
genomes. We employ a large-scale comparative genomics approach to predict> 40,000 …

[HTML][HTML] A Comprehensive Review of Bioinformatics Tools for Genomic Biomarker Discovery Driving Precision Oncology

AJ Clark, JW Lillard Jr - Genes, 2024 - mdpi.com
The rapid advancement of high-throughput technologies, particularly next-generation
sequencing (NGS), has revolutionized cancer research by enabling the investigation of …

Identifying small open reading frames in prokaryotes with ribosome profiling

N Vazquez-Laslop, CM Sharma, A Mankin… - Journal of …, 2022 - Am Soc Microbiol
Small proteins encoded by open reading frames (ORFs) shorter than 50 codons (small
ORFs [sORFs]) are often overlooked by annotation engines and are difficult to characterize …

A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond

M Pepe, M Hesami, KA de la Cerda, ML Perreault… - Biotechnology …, 2023 - Elsevier
Psychedelic mushrooms containing psilocybin and related tryptamines have long been used
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …