The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Diabetic retinopathy, one of the most devastating complications of diabetes, is a
multifactorial progressing disease with a very complex etiology. Although many metabolic …

Lipid metabolic abnormalities have emerged as potential risk factors for the development
and progression of diabetic complications, including diabetic retinopathy (DR). This review …

Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults across the
world. The pathogenesis of DR is multifactorial and the molecular mechanisms are still not …

Diabetic wounds (DW) constitute a substantial burden on global healthcare owing to their
widespread occurrence as a complication of diabetes. Angiogenesis, a crucial process …

Diabetic retinopathy (DR) affects over 93 million people worldwide and is the number one
cause of blindness among working age adults. These indicators coupled with the projected …

In the last decade, miRNAs have received substantial attention as potential players of
diabetes microvascular complications, affecting the kidney, the retina, and the peripheral …

Aim: Myocardial fibrosis is a well-established cause of increased myocardial stiffness and
subsequent diastolic dysfunction in the diabetic heart. The molecular regulators that drive …

The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and
ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular …

Genes, dietary, and lifestyle factors have been shown to be important in the pathophysiology
of diabetes and associated microvascular complications. Epigenetic modifications, such as …