As with most organ systems that undergo continuous generation and maturation during the
transition from fetal to adult life, the hematopoietic and immune systems also experience …

Background: Metabolic reprogramming is a hallmark of pulmonary arterial hypertension.
Platelet activation has been implicated in pulmonary arterial hypertension (PAH), whereas …

Inflammation is central to the pathogenesis of pulmonary vascular remodeling and
pulmonary hypertension (PH). Inflammation precedes remodeling in preclinical models, thus …

Pulmonary hypertension (PH) is a pathophysiological condition of increased pulmonary
circulation vascular resistance due to various reasons, which mainly leads to right heart …

Objective To evaluate whether transfusions in infants born preterm contribute to the
pathogenesis of bronchopulmonary dysplasia (BPD). Study design We conducted a …

Pulmonary hypertension (PH) is a progressive disease marked by pulmonary vascular
remodeling and right ventricular failure. Inflammation and oxidative stress are critical in PH …

The extracellular isoform of superoxide dismutase (SOD3) is decreased in patients and
animals with pulmonary hypertension (PH). The human R213G single-nucleotide …

Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) is a potent pulmonary vasoconstrictor and
contributes to high pulmonary vascular resistance in the developing ovine lung. In …

Schistosomiasis-induced pulmonary hypertension (PH) presents a significant global health
burden, yet the underlying mechanisms remain poorly understood. Here, we investigate the …

Hypoxia is considered to be a stressful physiological condition, which may occur during
labor and the later stages of pregnancy as a result of, among other reasons, an aged …