This paper presents a review of the recent literature covering separations of enantiomers
achieved with supercritical fluid chromatography (SFC) or subcritical fluid chromatography …

Method screening is an integral part of chromatographic method development for the
separation of racemates. Due to the highly complex retention mechanism of a chiral …

Enantioselective chromatography has been the preferred technique for the determination of
enantiomeric excess across academia and industry. Although sequential multicolumn …

Recent developments in supercritical fluid chromatography (SFC) have highlighted the
applicability of this technique for the analysis of highly polar compounds. The combination of …

Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Chiral separation remains an important area of research in analytical chemistry. This review
recognises the use of different chiral selectors for chiral liquid chromatography and capillary …

Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and
food additives are being commercialized as racemic mixtures, although in most cases only …

Conspectus Manufacturing process development of new drug substances in the
pharmaceutical industry combines numerous chemical challenges beyond the efficient …

During the last years, supercritical fluid chromatography (SFC) has attracted a continuously
growing number of users. Thanks to the introduction of state-of-the-art equipment, this …

Polyimine macrocycles are a new class of organic macrocycles with cyclic structures, well-
defined molecular cavities, and multiple cooperative binding sites, which have recently …