Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …

In recent years, bone tissue engineering has emerged as a promising solution to the
limitations of current gold standard treatment options for bone related-disorders such as …

Organ and tissue loss through disease and injury motivate the development of therapies that
can regenerate tissues and decrease reliance on transplantations. Regenerative medicine …

Alginate is a commonly used bioink in 3D bioprinting. Matrix stiffness is a key determinant of
mesenchymal stem cell (MSC) differentiation, suggesting that modulation of alginate bioink …

The rising incidence of bone disorders has resulted in the need for more effective therapies
to meet this demand, exacerbated by an increasing ageing population. Bone tissue …

Bone is a complex and hierarchical tissue consisting of nano hydroxyapatite and collagen
as major portion. Several attempts have been made to prepare the artificial bone so as to …

Significant progress has been made in the field of cartilage and bone tissue engineering
over the last two decades. As a result, there is real promise that strategies to regenerate …

The effectiveness of stem cell therapies has been hampered by cell death and limited
control over fate. These problems can be partially circumvented by using macroporous …

Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …

Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …