The mammalian respiratory system—the trachea and the lungs—arises from the anterior
foregut through a sequence of morphogenetic events involving reciprocal endodermal …

Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of
endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals …

Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is the most widely
used antioxidant in automobile tyres and many rubber products. We investigated the impact …

Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …

During development, animals generate distinct cell populations with specific identities,
functions, and morphologies. We mapped transcriptionally distinct populations across …

Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients.
Many questions remain regarding the function of macrophages in normal clearance of …

Perfluoropolyether carboxylic acids (PFECAs, CF 3 (OCF 2) n COO−, n= 2–5) are novel
alternatives to perfluorooctanoic acid (PFOA) and are widely used in industrial production …

Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …

Thyroid hormone system disruption (THSD) negatively affects multiple developmental
processes and organs. In fish, inhibition of deiodinases, which are enzymes crucial for (in) …

The fish swimbladder is a unique organ in vertebrate evolution and it functions for regulating
buoyancy in most teleost species. It has long been postulated as a homolog of the tetrapod …