Advancement in solubilization approaches: a step towards bioavailability enhancement of poorly soluble drugs
L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …
is currently a major hurdle in bringing new drug molecules to the market. According to some …
[PDF][PDF] A review on marketed Carica papaya leaf extract (CPLE) supplements for the treatment of dengue fever with thrombocytopenia and its drawback
S Mandal, DV Jaiswal, K Shiva - International Journal of …, 2020 - researchgate.net
Aim: In this review, there is detail description of the supplements present in the market for the
treatment of dengue a deadly viral disease. According to WHO survey, 40% of the …
treatment of dengue a deadly viral disease. According to WHO survey, 40% of the …
Micronization in food processing: A comprehensive review of mechanistic approach, physicochemical, functional properties and self-stability of micronized food …
A Dhiman, PK Prabhakar - Journal of Food Engineering, 2021 - Elsevier
Micronization is a mechanical and high shearing operation to downsize the particles of food
material to the micron range. Conventionally micronization techniques were employed in …
material to the micron range. Conventionally micronization techniques were employed in …
Nanonization techniques to overcome poor water-solubility with drugs
FLO Da Silva, MBDF Marques, KC Kato… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Most drugs used in therapy have low water-solubility, a factor that could reduce
their dissolution rate and oral bioavailability, representing a challenge in pharmaceutical …
their dissolution rate and oral bioavailability, representing a challenge in pharmaceutical …
Supercritical fluid technologies for the incorporation of synthetic and natural active compounds into materials for drug formulation and delivery
Various active compounds isolated from natural sources exhibit remarkable benefits, making
them attractive for pharmaceutical and biomedical applications, such as antioxidant …
them attractive for pharmaceutical and biomedical applications, such as antioxidant …
Cocrystals by design: a rational coformer selection approach for tackling the API problems
Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and
stability present a significant challenge during their processing into final dosage forms …
stability present a significant challenge during their processing into final dosage forms …
Measuring solubility of a chemotherapy-anti cancer drug (busulfan) in supercritical carbon dioxide
M Pishnamazi, S Zabihi, S Jamshidian… - Journal of Molecular …, 2020 - Elsevier
In the current study, the solubility of busulfan which is a chemotherapy drug for treating
chronic myelogenous leukemia (CML) is measured in supercritical carbon dioxide (SC-CO …
chronic myelogenous leukemia (CML) is measured in supercritical carbon dioxide (SC-CO …
Challenges in oral drug delivery of antiretrovirals and the innovative strategies to overcome them
A Sosnik, R Augustine - Advanced drug delivery reviews, 2016 - Elsevier
Abstract Development of novel drug delivery systems (DDS) represents a promising
opportunity to overcome the various bottlenecks associated with the chronic antiretroviral …
opportunity to overcome the various bottlenecks associated with the chronic antiretroviral …
Exploring the temperature-dependent proportions of lidocaine conformers equilibria in supercritical carbon dioxide via NOESY
This research determined the proportions of lidocaine conformer groups in a supercritical
carbon dioxide environment at constant pressures (10, 20 and 30 MPa) and temperatures of …
carbon dioxide environment at constant pressures (10, 20 and 30 MPa) and temperatures of …
Bicalutamide anticancer activity enhancement by formulation of soluble inclusion complexes with cyclodextrins
Bicalutamide (BCL) is a nonsteroidal antiandrogen drug that represents an alternative to
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …
castration in the treatment of prostate cancer, due to its relatively long half-life and tolerable …