Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host

JD Maya, BK Cassels, P Iturriaga-Vásquez… - … and Physiology Part A …, 2007 - Elsevier
Current knowledge of the biochemistry of Trypanosoma cruzi has led to the development of
new drugs and the understanding of their mode of action. Some trypanocidal drugs such as …

Opuntia (Cactaceae) plant compounds, biological activities and prospects–A comprehensive review

CE Aruwa, SO Amoo, T Kudanga - Food Research International, 2018 - Elsevier
Opuntia species are utilized as local medicinal interventions for chronic diseases and as
food sources mainly because they possess nutritional properties and biological activities …

In vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms

LG Magalhães, CB Machado, ER Morais… - Parasitology …, 2009 - Springer
The in vitro schistosomicidal activity of curcumin (doses ranging from 5 to 100 μM) was
carried out against Schistosoma mansoni adult worms. Curcumin (at 50 and 100 μM) …

[HTML][HTML] In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia DC (Asteraceae)

AA da Silva Filho, DO Resende, MJ Fukui, FF Santos… - Fitoterapia, 2009 - Elsevier
Baccharis dracunculifolia (Asteraceae), the most important plant source of the Brazilian
green propolis (GPE), displayed in vitro activity against Leishmania donovani, with an IC50 …

An Ethnopharmacological, Phytochemical and Pharmacological Review on Lignans from Mexican Bursera spp.

MC Marcotullio, M Curini, JX Becerra - Molecules, 2018 - mdpi.com
The genus Bursera belongs to the family Burseraceae and has been used in traditional
Mexican medicine for treating various pathophysiological disorders. The most representative …

Continuous-flow synthesis of polysubstituted γ-butyrolactones via enzymatic cascade catalysis

L Chu, X Zhang, J Li, X Deng, M Wu, Y Cheng… - Chinese Chemical …, 2024 - Elsevier
Polysubstituted chiral γ-butyrolactones are the core structural units of many natural products
and high value-added flavors and fragrances used in the food and cosmetic industry …

Immunomodulatory and Antileishmanial Activity of Phenylpropanoid Dimers Isolated from Nectandra leucantha

TA Costa-Silva, SS Grecco, FS De Sousa… - Journal of natural …, 2015 - ACS Publications
Three phenylpropanoid dimers (1–3) including two new metabolites were isolated from the
extract of the twigs of Nectandra leucantha using antileishmanial bioassay-guided …

Justicidin B: a promising bioactive lignan

S Hemmati, H Seradj - Molecules, 2016 - mdpi.com
Adverse effects and drug resistance to the current onchopharmacologicals have increased
the demand for alternative novel therapeutics. We herein introduce justicidin B, an …

In vitro and in vivo antileishmanial activities of a Brazilian green propolis extract

K Pontin, AA Da Silva Filho, FF Santos, MLA Silva… - Parasitology …, 2008 - Springer
The in vitro antileishmanial activity of Brazilian green propolis hydroalcoholic extract (BPE)
were carried out on Leishmania (Viannia) braziliensis against both promastigote (doses …

In vitro antileishmanial and antitrypanosomal activity of compounds isolated from the roots of Zanthoxylum tingoassuiba

RS Costa, OP Souza Filho, OCS Dias… - Revista Brasileira de …, 2018 - SciELO Brasil
Abstract Five coumarins (5, 7, 8-trimethoxycoumarin (1), sabandin (2), cubreuva lactone (3),
5, 7-dimethoxycoumarin (5) and braylin (6)), seven furoquinoline alkaloids (isopimpinelin …