Ergosterol is an essential component of fungal cell membranes that determines the fluidity,
permeability and activity of membrane-associated proteins. Ergosterol biosynthesis is a …

Following the acquisition of chloroplasts and mitochondria by eukaryotic cells during
endosymbiotic evolution, most of the genes in these organelles were either lost or …

A biofilm is a surface-associated population of microorganisms embedded in a matrix of
extracellular polymeric substances. Biofilms are a major natural growth form of …

Prion proteins undergo self-sustaining conformational conversions that heritably alter their
activities. Many of these proteins operate at pivotal positions in determining how genotype is …

Yeast is an ideal organism for the development and application of synthetic biology, yet
there remain relatively few well-characterised biological parts suitable for precise …

Abstract Changes in oxygen levels cause widespread changes in gene expression in
organisms ranging from bacteria to humans. In Saccharomyces cerevisiae, this response is …

Two novel ergosterol derivatives, ganodermasides A and B, hydroxylated at C-15 were
isolated from the methanol extract of spores of a medicinal mushroom, Ganoderma lucidum …

The cell wall of Candida albicans lies at the crossroads of pathogenicity and therapeutics. It
contributes to pathogenicity through adherence and invasion; it is the target of both chemical …

Background Gene co-expression networks are often constructed by computing some
measure of similarity between expression levels of gene transcripts and subsequently …

Terpenoids comprise various structures conferring versatile functions to eukaryotes, for
example in the form of prenyl-anchors they attach proteins to membranes. The physiology of …