Biophysical chemistry behind sickle cell anemia and the mechanism of voxelotor action

M Suhail - Scientific Reports, 2024 - nature.com
Sickle cell anemia disease has been a great challenge to the world in the present situation.
It occurs only due to the polymerization of sickle hemoglobin (HbS) having Pro–Val–Glu …

[HTML][HTML] Anti sickling potential and chemical profiling of traditionally used Woodfordia fruticosa (L.) Kurz leaves

S Mishra, S Sonter, MK Dwivedi, PK Singh - Arabian Journal of Chemistry, 2022 - Elsevier
Woodfordia fruticosa (L.) Kurz is a widely used plant in traditional medicine systems. The
tribal communities of Amarkantak, Madhya Pradesh (India) are using this plant for the …

[PDF][PDF] Sickle hemoglobin polymerization inhibition and antisickling medicinal plants

F Ohiagu, P Chikezie, C Chikezie - J. Phytopharmacol, 2021 - phytopharmajournal.com
Sickle cell disease (SCD) is a dilapidating disorder that is associated with organ destruction
and decreased life expectancy. Therapeutic remedies that lead to fundamental cure of SCD …

[PDF][PDF] Effect of Aspartame on Hemoglobin in Sickle Cell Anemia

TK Behera, JR Behera, A Mishra, S Madhual - gene, 2024 - iijls.com
Background: Sickle cell disease (SCD) is a monogenic disorder characterized by aberrant
hemoglobin S (Hb S) due to an A-to-T mutation in the β-globin gene. This leads to …

[PDF][PDF] MALAYSIAN JOURNAL OF BIOCHEMISTRY & MOLECULAR BIOLOGY

KI Ijoma, VIE Ajiwe, JO Ndubuisi - researchgate.net
Accepted: 7 November 2022 Sickle cell anemia is a hereditary genetic disease caused by
the substitution of glutamic acid by valine at beta six (β-6) position of the hemoglobin; the …