Glutamate receptors have been identified as important interfaces in learning and memory
paradigms as well as in mechanisms of synaptic plasticity, such as long‐term potentiation …

One of the reasons that cyclopropyl-group-containing R-amino acids play an outstanding
role in biologically important processes, the synthesis of peptide mimetics and modern drug …

The postnatal expression of metabotropic glutamate receptors was studied in rat brain byin
situ hybridization and autoradiographic binding techniques. The messenger RNAs encoding …

Metabotropic glutamate receptors are important mediators of excitatory amino acid
neurotransmission in the striatum. Two-color immunofluorescence histochemistry and …

We used cultured cerebellar granule cells to examine whether native group‐III metabotropic
glutamate (mGlu) receptors are coupled to the mitogen‐activated protein kinase (MAPK) and …

Abstract (2S, 1′ R, 2′ R, 3′ R)-2-(2, 3-Dicarboxycyclopropyl) glycine (DCG-IV), a potent
agonist of subtypes 2 and 3 of metabotropic glutamate receptors (mGluR2 or 3), protected …

1 Activation of metabotropic glutamate receptors (mGluRs) in hippocampal CA1 pyramidal
neurones leads to a depolarization, an increase in input resistance and a reduction in spike …

Abstract Major Depressive Disorder (MDD) is a serious neuropsychiatric disorder afflicting
around 16–17% of the global population and is accompanied by recurrent episodes of low …

Since the initial discovery that the amino acid β-N-methylamino-L-alanine (BMAA) was a
neurotoxin, a great deal has been learned about its mechanism of action. However, exactly …

Anticonvulsive and neuroprotective effects of (2S, 1′ R, 2′ R, 3′ R)-2-(2, 3-
dicarboxycyclopropyl) glycine (DCG-IV), a potent agonist for Group II metabotropic …