Cancer growth represents a dysregulated imbalance between cell gain and cell loss, where
the rate of proliferating mutant tumour cells exceeds the rate of those that die. Apoptosis, the …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Glioblastoma (GBM) is one of the most aggressive and lethal human brain tumors. At
present, GBMs are divided in primary and secondary on the basis of the mutational status of …

Glioblastomas (glioblastoma multiforme, GBM) are one of the most recalcitrant brain tumors
because of their aggressive invasive growth and resistance to therapy. They are highly …

Glioblastoma multiforme (GBM), a grade IV astrocytoma, is the most common and deadly
type of primary malignant brain tumor, with a patient's median survival rate ranging from 15 …

Glioblastoma multiforme is a central nervous system tumor of grade IV histological
malignancy according to the WHO classification. Over 90% of diagnosed glioblastomas …

Aggressive cancers such as glioblastoma (GBM) contain intermingled apoptotic cells
adjacent to proliferating tumor cells. Nonetheless, intercellular signaling between apoptotic …

The niche concept was originally developed to describe the location of normal neural stem
cells (NSCs) in the subependymal layer of the sub-ventricular zone. In this paper, its …

Proliferating embryonic and cancer cells preferentially use aerobic glycolysis to support
growth, a metabolic alteration commonly referred to as the “Warburg effect.” Here, we show …

Glioblastoma (GBM) is the most common brain tumor in adults and the mesenchymal GBM
subtype was reported to be the most malignant, presenting severe hypoxia and necrosis …