Mechanisms of stereodirecting participation and ester migration from near and far in glycosylation and related reactions

AA Hettikankanamalage, R Lassfolk, FS Ekholm… - Chemical …, 2020 - ACS Publications
This review is the counterpart of a 2018 Chemical Reviews article (Adero, PO; Amarasekara,
H.; Wen, P.; Bohé, L.; Crich, D. Chem. Rev. 2018, 118, 8242–8284) that examined the …

“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates

SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

Automated solution-phase multiplicative synthesis of complex glycans up to a 1,080-mer

W Yao, DC Xiong, Y Yang, C Geng, Z Cong, F Li… - Nature …, 2022 - nature.com
Carbohydrates play essential roles in nature, such as in cell–cell communication, cell growth
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …

Human milk oligosaccharides (HMOS): structure, function, and enzyme-catalyzed synthesis

X Chen - Advances in carbohydrate chemistry and biochemistry, 2015 - Elsevier
The important roles played by human milk oligosaccharides (HMOS), the third major
component of human milk, in the health of breast-fed infants have been increasingly …

Enzymatic and cell factory approaches to the production of human milk oligosaccharides

M Faijes, M Castejón-Vilatersana, C Val-Cid… - Biotechnology …, 2019 - Elsevier
Infant formula milk companies try to develop fortified formula milk that mimics human milk as
closely as possible, since it is well-known that breast milk has considerable implications in …

Enzymatic and chemoenzymatic synthesis of human milk oligosaccharides and derivatives

J Zheng, H Xu, J Fang, X Zhang - Carbohydrate Polymers, 2022 - Elsevier
Human milk oligosaccharides (HMOs) are complex glycans that are the third largest solid
component in human milk. It has attracted great interest in recent years due to their critical …

Venturing beyond donor-controlled glycosylation: new perspectives toward anomeric selectivity

WL Leng, H Yao, JX He, XW Liu - Accounts of Chemical Research, 2018 - ACS Publications
Conspectus Glycans are complex compounds consisting of sugars linked glycosidically,
existing either as pure polysaccharides or as part of glycoconjugates. They are prevalent in …

Understanding the chemistry and biology of glycosylation with glycan synthesis

L Krasnova, CH Wong - Annual review of biochemistry, 2016 - annualreviews.org
Glycoscience research has been significantly impeded by the complex compositions of the
glycans present in biological molecules and the lack of convenient tools suitable for studying …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010

DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

[HTML][HTML] Silyl-protective groups influencing the reactivity and selectivity in glycosylations

M Bols, CM Pedersen - Beilstein journal of organic chemistry, 2017 - beilstein-journals.org
Silyl groups such as TBDPS, TBDMS, TIPS or TMS are well-known and widely used alcohol
protective groups in organic chemistry. Cyclic silylene protective groups are also becoming …