Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions
K Reemst, L Kracht, JM Kotah, R Rahimian… - Translational …, 2022 - nature.com
Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including
depression later in life. Neuroinflammatory processes have been implicated in ELS-induced …
depression later in life. Neuroinflammatory processes have been implicated in ELS-induced …
Association between early life adversity and allostatic load in girls with precocious puberty
J Li, Y Yu, J Yuan, D Liu, J Fang, P Wu, Y Zhou… - …, 2023 - Elsevier
Context The mechanisms underlying the elevated long-term health risk in girls with
precocious puberty remain unclear, but might result from physiological wear and tear …
precocious puberty remain unclear, but might result from physiological wear and tear …
Gender medicine and sleep disorders: from basic science to clinical research
E Perger, R Silvestri, E Bonanni, MC Di Perri… - Frontiers in …, 2024 - frontiersin.org
Several pivotal differences in sleep and sleep disorders are recognized between women
and men. This is not only due to changes in hormonal balance during women's reproductive …
and men. This is not only due to changes in hormonal balance during women's reproductive …
Current perspectives on perinatal mental health and neurobehavioral development: focus on regulation, coregulation and self-regulation
BRH Van den Bergh, MC Antonelli… - Current Opinion in …, 2024 - journals.lww.com
During the perinatal period, addressing vulnerable contexts and building resilient systems
may promote neurobehavioral development. A pluralistic approach to research, taking a …
may promote neurobehavioral development. A pluralistic approach to research, taking a …
Maternal stress is associated with higher protein-bound amino acid concentrations in human milk
HG Juncker, EFG Naninck, BJ van Keulen… - Frontiers in …, 2023 - frontiersin.org
Background Maternal stress in the postpartum period affects not only the mother but also her
newborn child, who is at increased risk of developing metabolic and mental disorders later …
newborn child, who is at increased risk of developing metabolic and mental disorders later …
[HTML][HTML] Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice
J Geertsema, M Kratochvil, R González-Domínguez… - Neurobiology of …, 2024 - Elsevier
Stress exposure during the sensitive period of early development has been shown to
program the brain and increases the risk to develop cognitive deficits later in life. We have …
program the brain and increases the risk to develop cognitive deficits later in life. We have …
Metabolic effects of early life stress and pre‐pregnancy obesity are long lasting and sex specific in mice
LM Brix, D Monleon, MC Collado… - European Journal of …, 2023 - Wiley Online Library
Early life stress (ELS) is associated with metabolic, cognitive, and psychiatric diseases and
has a very high prevalence, highlighting the urgent need for a better understanding of the …
has a very high prevalence, highlighting the urgent need for a better understanding of the …
[HTML][HTML] Molecular underpinnings of programming by early-life stress and the protective effects of early dietary ω6/ω3 ratio, basally and in response to LPS: Integrated …
K Reemst, N Lopizzo, MR Abbink… - Brain, behavior, and …, 2024 - Elsevier
Early-life stress (ELS) exposure increases the risk for mental disorders, including cognitive
impairments later in life. We have previously demonstrated that an early diet with low ω6/ω3 …
impairments later in life. We have previously demonstrated that an early diet with low ω6/ω3 …
Improving Sleep to Improve Stress Resilience
Abstract Purpose of Review The neuroendocrine stress response is a natural process of our
body which, however, might become toxic if not properly turned on and off. Resilience is the …
body which, however, might become toxic if not properly turned on and off. Resilience is the …
[HTML][HTML] The dynamic influence of nutrition on prolonged cognitive healthspan across the life course: a perspective review
Cognitive function undergoes a dynamic trajectory across the lifespan, influenced by
multifaceted mechanisms encompassing genetics, lifestyle, and environmental factors. This …
multifaceted mechanisms encompassing genetics, lifestyle, and environmental factors. This …