Obstructive sleep apnea syndrome (OSAS) is characterized by intermittent hypoxia (IH)
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …

Obstructive sleep apnea (OSA) is a common syndrome that features a complex etiology and
set of mechanisms. Here we summarized the molecular pathogenesis of OSA, especially the …

Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic
lupus erythematosus, Crohn's disease, periodontitis, and carcinoma metastasis frequently …

Chronic intermittent hypoxia (CIH, a model for sleep apnoea) is a major risk factor for several
cardiovascular diseases. Autonomic imbalance (sympathetic overactivity and …

Obstructive sleep apnea (OSA) is a chronic and highly prevalent condition that is associated
with oxidative stress, inflammation, and fibrosis, leading to endothelial dysfunction, arterial …

Objectives Obesity-induced insulin resistance (IR) is known to influence hepatic cytokines
(hepatokines), including fibroblast growth factor (FGF-21), fetuin-A, and chemerin. This study …

Maternal obesity (MO) is associated with offspring cardiometabolic diseases that are
hypothesized to be partly mediated by glucocorticoids. Therefore, we aimed to study fetal …

Advances in the treatment of hemophilia have increased the life expectancy of this
population and we are currently facing diseases associated with aging, including …

Purpose Chronic intermittent hypoxia (CIH) related arterial endothelium injury is a common
cause of cardiovascular system injury. However, the mechanism still needs to be clarified. In …

Plasminogen activator inhibitor-1 (PAI-1) has a significant role in fibrinolysis, atherogenesis,
cellular senescence, and chronic inflammation. OSA (obstructive sleep apnea) leads to …