Molecular pathology, oxidative stress, and biomarkers in obstructive sleep apnea
PG Meliante, F Zoccali, F Cascone… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is characterized by intermittent hypoxia (IH)
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …
Advances in molecular pathology of obstructive sleep apnea
M Zhang, Y Lu, L Sheng, X Han, L Yu, W Zhang, S Liu… - Molecules, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a common syndrome that features a complex etiology and
set of mechanisms. Here we summarized the molecular pathogenesis of OSA, especially the …
set of mechanisms. Here we summarized the molecular pathogenesis of OSA, especially the …
The Roles of Fibrinolytic Factors in Bone Destruction Caused by Inflammation
Y Kanno - Cells, 2024 - mdpi.com
Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic
lupus erythematosus, Crohn's disease, periodontitis, and carcinoma metastasis frequently …
lupus erythematosus, Crohn's disease, periodontitis, and carcinoma metastasis frequently …
Chronic intermittent hypoxia remodels catecholaminergic nerve innervation in mouse atria
A Bizanti, Y Zhang, Z Toledo… - The Journal of …, 2024 - Wiley Online Library
Chronic intermittent hypoxia (CIH, a model for sleep apnoea) is a major risk factor for several
cardiovascular diseases. Autonomic imbalance (sympathetic overactivity and …
cardiovascular diseases. Autonomic imbalance (sympathetic overactivity and …
Cardiovascular Disease in Obstructive Sleep Apnea: Putative Contributions of Mineralocorticoid Receptors
Obstructive sleep apnea (OSA) is a chronic and highly prevalent condition that is associated
with oxidative stress, inflammation, and fibrosis, leading to endothelial dysfunction, arterial …
with oxidative stress, inflammation, and fibrosis, leading to endothelial dysfunction, arterial …
Association of hepatokines with markers of endothelial dysfunction and vascular reactivity in obese adolescents
D Stein, D Ovadia, S Katz, PC Brar - Journal of Pediatric …, 2024 - degruyter.com
Objectives Obesity-induced insulin resistance (IR) is known to influence hepatic cytokines
(hepatokines), including fibroblast growth factor (FGF-21), fetuin-A, and chemerin. This study …
(hepatokines), including fibroblast growth factor (FGF-21), fetuin-A, and chemerin. This study …
Dysregulation of Glucocorticoid Receptor Homeostasis and Glucocorticoid-Associated Genes in Umbilical Cord Endothelial Cells of Diet-Induced Obese Pregnant …
E Mata-Greenwood, WL Chow, NAO Anti… - International Journal of …, 2024 - mdpi.com
Maternal obesity (MO) is associated with offspring cardiometabolic diseases that are
hypothesized to be partly mediated by glucocorticoids. Therefore, we aimed to study fetal …
hypothesized to be partly mediated by glucocorticoids. Therefore, we aimed to study fetal …
Atherosclerosis in Patients with Congenital Hemophilia: A Focus on Peripheral Artery Disease
Advances in the treatment of hemophilia have increased the life expectancy of this
population and we are currently facing diseases associated with aging, including …
population and we are currently facing diseases associated with aging, including …
Ferrostatin-1 Reversed Chronic Intermittent Hypoxia-Induced Ferroptosis in Aortic Endothelial Cells via Reprogramming Mitochondrial Function
J Chen, X Deng, T Lin, J Huang, Y Yang… - Nature and Science of …, 2024 - Taylor & Francis
Purpose Chronic intermittent hypoxia (CIH) related arterial endothelium injury is a common
cause of cardiovascular system injury. However, the mechanism still needs to be clarified. In …
cause of cardiovascular system injury. However, the mechanism still needs to be clarified. In …
The Curious Role of PAI-1 in Severe Obstructive Sleep Apnea
Plasminogen activator inhibitor-1 (PAI-1) has a significant role in fibrinolysis, atherogenesis,
cellular senescence, and chronic inflammation. OSA (obstructive sleep apnea) leads to …
cellular senescence, and chronic inflammation. OSA (obstructive sleep apnea) leads to …