The TP53 tumor suppressor is the most frequently altered gene in human cancers, and has
been a major focus of oncology research. The p53 protein is a transcription factor that can …

Elevated triglycerides and non-high-density lipoprotein cholesterol (HDL-C) are risk factors
for atherosclerotic cardiovascular disease (ASCVD). ARO-ANG3 is an RNA interference …

The global outbreak of COVID-19 possesses serious challenges and adverse impacts for
patients with progression of chronic liver disease and has become a major threat to public …

Background Antitumor T cell immunotherapy as a novel cancer therapeutic strategy has
shown enormous promise. However, the tumor microenvironment (TME) is characterized by …

The combination of programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte
antigen 4 (CTLA-4) antibodies has potential for enhancing clinical efficacy. We described …

Using conventional immunoglobulin G (IgG) molecules as therapeutic agents presents
several well-known disadvantages owing to their large size and structural complexity …

The aim of this review is to summarize some of the most recent work in the field of
cardiovascular disease (CVD) diagnosis and therapy, focusing mainly on the role of …

Atherosclerosis (AS) ultimately cause major adverse cardiovascular events (MACEs). While
traditional strategies by lipid-reducing have reduced MACEs, many patients continue to face …

Abstract Aflatoxin B1 (AFB 1), a ubiquitous and toxic mycotoxin in human food and animal
feedstuff, can impair the function and health of some organs, especially the liver. However …

Objective Blood lipid levels play a critical role in the progression of atherosclerosis.
However, even with adequate lipid reduction, significant residual cardiovascular risk …