Technetium (I) carbonyl complexes for nuclear medicine: Coordination-chemical aspect

GV Sidorenko, AE Miroslavov, MY Tyupina - Coordination Chemistry …, 2023 - Elsevier
Studies concerning the development of radiopharmaceuticals based on the Tc (I) carbonyl
core are considered from the coordination-chemical viewpoint. The coordination behavior of …

Recent advances in the synthesis of (99mTechnetium) based radio-pharmaceuticals

K Shahzad, ASA Majid, M Khan, MA Iqbal… - Reviews in Inorganic …, 2021 - degruyter.com
Technetium radionuclide (99mTc) has excellent extent of disintegration properties and
occupies a special place in the field of nuclear medicinal chemistry and other health …

Synthesis and biological evaluation of novel 99mTc labeled ornidazole xanthate complexes as potential hypoxia imaging agents

Z Li, X Song, J Zhang - Journal of Radioanalytical and Nuclear Chemistry, 2015 - Springer
In this study, ornidazole xanthate (ONXT) ligand was successfully synthesized and its 99m
Tc-nitrido core, 99m Tc-oxo core and [99m Tc (CO) 3]+ core complexes were prepared with …

Biological evaluation and SPECT imaging of tumor hypoxia using a novel technetium-99m labeled tracer with 2-nitroimidazole moiety

X Lin, Q Ruan, L Lin, X Zhang, X Duan, Y Teng… - … of Radioanalytical and …, 2018 - Springer
To develop novel 99m Tc labeled nitroimidazole imaging agents for imaging tumor hypoxia,
99m Tc labeled ethylene diamine tetraacetic acid derivative of 4-nitroimidazole was reported …

Synthesis and preliminary biological evaluation of 99mTc(CO)3-labeled pegylated 2-nitroimidazoles

J Wang, X Zheng, W Wu, W Yang, Y Liu - Journal of Radioanalytical and …, 2014 - Springer
This work reports the synthesis, radiolabeling and preliminary biodistribution results in tumor-
bearing mice of 99m Tc (CO) 3-labeled pegylated (PEG) 2-nitroimidazoles for tumor hypoxia …

Preparation and biological evaluation of a technetium-99m labeled 4-nitroimidazole derivative for imaging tumor hypoxia

X Lin, S Fang, Y Teng, J Zhang - Journal of Radioanalytical and Nuclear …, 2017 - Springer
A novel ethylene diamine tetraacetic acid derivative of 4-nitroimidazole (EDTA-4-EtNHNM)
was successfully synthesized as a carrier molecule and it was radiolabeled with 99m Tc in …

Synthesis, 99mTc(CO)3-labeling and preliminary biodistribution studies of a novel colchicine complex

J Wang, X Duan, H Mao, J Yang, C Tan, Y Tian… - … of Radioanalytical and …, 2013 - Springer
This work reports the synthesis, radiolabeling and preliminary biodistribution results in tumor-
bearing mice of [99m Tc (CO) 3 (PA-TZ-CHC)]+. The novel colchicine (CHC) ligand was …

Radiochemistry

DS Urch - Annual Reports Section" A"(Inorganic Chemistry), 2013 - pubs.rsc.org
In this year's review of recent progress in radiochemistry, new radiochemical methods for
isotope production, advances in labelling procedures, radioactive isotopes in the …

Radiosynthesis and preliminary biological evaluation of 99mTc-labeled 2-methyl-2-pentylmalonic acid as an apoptosis imaging agent

S Mushtaq, J Jeon, JA Kang, YR Nam, BS Jang… - … of Radioanalytical and …, 2017 - Springer
Apoptosis is one of the fundamental phenomena behind successful radiation and
chemotherapy treatments. Non-invasive imaging of apoptosis can offer an early diagnosis of …

[图书][B] Technetium-99m carbonyl complexes and new ligand development for targeted radiopharmaceuticals

TR Hayes - 2016 - search.proquest.com
Abstract 99m Tc is the primary radioisotope used for diagnostic imaging in nuclear medicine.
Targeted imaging with 99m Tc involves the attachment of the metal using a bifunctional …