In 2009, the Clinical Pharmacogenetics Implementation Consortium (CPIC, www. cpicpgx.
org), a shared project between Pharmacogenomics Knowledge Base (PharmGKB …

Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for
immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of …

Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …

Purpose Existing pharmacogenomic informatics models, key implementation steps, and
emerging resources to facilitate the development of pharmacogenomic clinical decision …

Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …

Vanderbilt University Medical Center implemented pharmacogenomics (PGx) testing with
the Pharmacogenomic Resource for Enhanced Decisions in Care and Treatment …

Precision medicine (PM) is an emerging approach that appears with the impression of
changing the existing paradigm of medical practice. Recent advances in technological …

Successfully implementing pharmacogenomics into routine clinical practice requires an
efficient process to order genetic tests and report the results to clinicians and patients. Lack …

Adverse drug reactions (ADRs) are common, are associated with morbidity and mortality,
and are costly to healthcare systems. Genomic factors predispose to ADRs, but these vary …