Harnessing genomics for delineating conservation units
Genomic data have the potential to revolutionize the delineation of conservation units (CUs)
by allowing the detection of adaptive genetic variation, which is otherwise difficult for rare …
by allowing the detection of adaptive genetic variation, which is otherwise difficult for rare …
Genomics and the future of conservation genetics
We will soon have complete genome sequences from thousands of species, as well as from
many individuals within species. This coming explosion of information will transform our …
many individuals within species. This coming explosion of information will transform our …
[图书][B] Who we are and how we got here: Ancient DNA and the new science of the human past
D Reich - 2018 - books.google.com
The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …
humans. This important new data has added to our knowledge from archaeology and …
[HTML][HTML] Reconstructing prehistoric African population structure
We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …
divergent lineage that comprises the primary ancestry of the southern African San had a …
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher …
conditions, including greater temperature extremes, different pathogens and higher …
Genetic evidence for two founding populations of the Americas
P Skoglund, S Mallick, MC Bortolini, N Chennagiri… - Nature, 2015 - nature.com
Genetic studies have consistently indicated a single common origin of Native American
groups from Central and South America,,,. However, some morphological studies have …
groups from Central and South America,,,. However, some morphological studies have …
[HTML][HTML] A map of human genome variation from population scale sequencing
1000 Genomes Project Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The 1000 Genomes Project aims to provide a deep characterisation of human
genome sequence variation as a foundation for investigating the relationship between …
genome sequence variation as a foundation for investigating the relationship between …
Natural selection and infectious disease in human populations
EK Karlsson, DP Kwiatkowski, PC Sabeti - Nature Reviews Genetics, 2014 - nature.com
The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …
genetic variation in modern populations, and this has important implications for the growing …
Population genomics of rapid adaptation by soft selective sweeps
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …
Robust identification of local adaptation from allele frequencies
Comparing allele frequencies among populations that differ in environment has long been a
tool for detecting loci involved in local adaptation. However, such analyses are complicated …
tool for detecting loci involved in local adaptation. However, such analyses are complicated …