Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

Mitochondria release many damage-associated molecular patterns (DAMPs) when cells are
damaged or stressed, with mitochondrial DNA (mtDNA) being. MtDNA activates innate …

Oxidative stress plays an important role in various renal and hepatic pathologies, and
reduction of oxidative stress-induced processes is an important protective strategy in tissues …

AIM: To evaluate preventative effects of ischemic preconditioning (IP) in a rat model of
intestinal injury induced by ischemia-reperfusion (IR). METHODS: Male Sprague-Dawley …

Aim of the study Mast cell (MC) degranulation contributes to the protection mediated by
ischemic preconditioning (IPC); however, the precise mechanisms underlying this protection …

Intestinal ischemia/reperfusion (I/R) injury is a critical condition associated with high
morbidity and mortality. Studies show that ischemic preconditioning (IPC) can protect the …

Pituitary adenylate cyclase activating polypeptide (PACAP) is a pleiotropic and
multifunctional neuropeptide. Numerous studies prove that PACAP has neuroprotective …

Ischemic preconditioning (IPC) has been considered to be a potential therapy to reduce
ischemia-reperfusion injury (IRI) since the 1980s. Our previous study indicated that …

Cold preservation prior to small‐bowel transplantation can moderate tissue injury, although
it is unable to protect the bowel graft from acute reperfusion injury. One method to reduce …

One of the well-known effects of pituitary adenylate cyclase activating polypeptide (PACAP)
is its neuroprotective and cytoprotective actions including renoprotective effects. Mice …