Redefining fundamental concepts of transcription initiation in bacteria

C Mejía-Almonte, SJW Busby, JT Wade… - Nature Reviews …, 2020 - nature.com
Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

Transcriptional activation by recruitment

M Ptashne, A Gann - Nature, 1997 - nature.com
The recruitment model for gene activation stipulates that an activator works by bringing the
transcriptional machinery to the DNA. Recent experiments in bacteria and yeast indicate that …

Nitrogen control in bacteria

MJ Merrick, RA Edwards - Microbiological reviews, 1995 - Am Soc Microbiol
Nitrogen metabolism in prokaryotes involves the coordinated expression of a large number
of enzymes concerned with both utilization of extracellular nitrogen sources and intracellular …

Protein phosphorylation and regulation of adaptive responses in bacteria

JB Stock, AJ Ninfa, AM Stock - Microbiological reviews, 1989 - Am Soc Microbiol
Bacteria continuously adapt to changes in their environment. Responses are largely
controlled by signal transduction systems that contain two central enzymatic components, a …

[HTML][HTML] Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli

MR Atkinson, MA Savageau, JT Myers, AJ Ninfa - Cell, 2003 - cell.com
Abstract Analysis of the system design principles of signaling systems requires model
systems where all components and regulatory interactions are known. Components of the …

How eukaryotic transcriptional activators work

M Ptashne - Nature, 1988 - nature.com
How eukaryotic transcriptional activators work Page 1 _N_A_TU_R_E_V_O_L_.
_33_5_2_0_0_C_T_O_B_E_R_19_8_8 _ _ _ _ _ _ _~ REVIEW ARTICLE--------------------683 …

Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective

WC van Heeswijk, HV Westerhoff… - … and Molecular Biology …, 2013 - Am Soc Microbiol
We present a comprehensive overview of the hierarchical network of intracellular processes
revolving around central nitrogen metabolism in Escherichia coli. The hierarchy intertwines …

Signal transduction schemes of bacteria

JS Parkinson - Cell, 1993 - Elsevier
When the Going Gets Tough, the Tough Get Going Life in the microbial world is no picnic.
Hard molecular rain falls incessantly from all sides, nutrients are scarce and unpredictable …

Phosphorylation of three proteins in the signaling pathway of bacterial chemotaxis

JF Hess, K Oosawa, N Kaplan, MI Simon - Cell, 1988 - cell.com
Six cytoplasmic the gene products are required for signal transduction in bacterial
chemotaxis, but the nature of their biochemical interactions is not known. We show that in …

Signal transduction in bacteria

JB Stock, AM Stock, JM Mottonen - Nature, 1990 - nature.com
Cells display a remarkable ability to respond to small fluctuations in their surroundings. In
simple microbial systems, information from sensory receptors feeds into a circuitry of …