The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …

Accumulating evidence shows that extracellular vesicles (EVs) produced by mesenchymal
stem/stromal cells (MSCs) exert their therapeutic effects in several disease models. We …

Recent observations have demonstrated that one of the functions of mesenchymal
stem/stromal cells (MSCs) is to serve as guardians against excessive inflammatory …

Quantitative assays for human DNA and mRNA were used to examine the paradox that
intravenously (iv) infused human multipotent stromal cells (hMSCs) can enhance tissue …

Previous reports suggested that culture as 3D aggregates or as spheroids can increase the
therapeutic potential of the adult stem/progenitor cells referred to as mesenchymal stem …

Multipotent mesenchymal stromal cells (MSCs) represent a rare heterogeneous subset of
pluripotent stromal cells that can be isolated from many different adult tissues that exhibit the …

The concept of mesenchymal stem cells (MSCs) is becoming increasingly obscure due to
the recent findings of heterogeneous populations with different levels of stemness within …

Mesenchymal stem cells (MSCs), as the most common cell source for stem cell therapy, play
an important role in the modulation of innate and adaptive immune responses and have …

Culturing cells in three dimension (3D) provides an insight into their characteristics in vivo.
We previously reported that human mesenchymal stem/stromal cells (hMSCs) cultured as …