Atherosclerotic cardiovascular disease is one of the leading causes of death worldwide.
Establishing animal models of atherosclerosis is of great benefit for studying its complicated …

Chronic inflammatory diseases are caused due to prolonged inflammation at a specific site
of the body. Among other inflammatory diseases, bacterial meningitis, chronic obstructive …

Background and aims Scavenger receptors form a superfamily of membrane-bound
receptors that bind and internalize different types of ligands, including pro-atherogenic …

Ulinastatin is widely used in the treatment of pancreatitis and sepsis, because of its excellent
anti-inflammatory and antioxidant effects. However, its effects on atherosclerosis, an …

Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes spinal
inflammation and fusion. Although the cause of AS is unknown, genetic factors (eg, HLA …

Background and aims ApoEb is a zebrafish homologous to mammalian ApoE, whose
deficiency would lead to lipid metabolism disorders (LMDs) like atherosclerosis. We …

Ectopic lipid accumulation in macrophages is responsible for the formation of macrophage
foam cells (MFCs) which are involved in the crosstalk with the perivascular adipose tissue …

A reduction in daily caloric or nutrient intake has been observed to promote health benefits
in mammals and other vertebrates. Feed Restriction (FR), whereby the overall food intake of …

Background Ezetimibe is known for its lipid-lowering safety and tolerability, but its real-world
adverse effects have not been fully evaluated. In this study, adverse events associated with …

Background: Ulcerative colitis is a chronic debilitating disease. The existing treatment,
including sulfasalazine, corticosteroids, azathioprine/6-mercaptopurine, cyclosporine, and …