B cells have a central role in many autoimmune diseases, including in those with renal
involvement, as well as in the immunological response to kidney transplantation. The …

Myasthenia gravis (MG) is a prototypical autoantibody mediated disease. The
autoantibodies in MG target structures within the neuromuscular junction (NMJ), thus …

B cells have important functions in the pathogenesis of autoimmune diseases, including
autoimmune rheumatic diseases. In addition to producing autoantibodies, B cells contribute …

Increasing recognition of the role of B cells in the adaptive immune response makes B cells
an important therapeutic target in autoimmunity. Numerous current and developmental …

Background & Aims Development of celiac disease is believed to involve the
transglutaminase-dependent response of CD4+ T cells toward deamidated gluten peptides …

B cells contribute to multiple aspects of autoimmune disorders, and B cell–targeting
therapies, including B cell depletion, have been proven to be efficacious in treatment of …

People identified with Black/African American or Hispanic/Latinx ethnicity are more likely to
exhibit a more severe multiple sclerosis disease course relative to those who identify as …

Exaggerated or inappropriate responses by B cells are an important feature in many types of
autoimmune neurological diseases. The recent success of B-cell depletion in the treatment …

Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous
system disorders mainly characterized by the presence of antibodies targeting neuronal or …

B cells play a pivotal role in the pathogenesis of autoimmune disease (AD) by the production
of autoantibodies, secretion of cytokines and presentation of autoantigens. As a pro-survival …