International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Comparative efficacy and safety of abrocitinib, baricitinib, and upadacitinib for moderate‐to‐severe atopic dermatitis: a network meta‐analysis

H Wan, H Jia, T Xia, D Zhang - Dermatologic Therapy, 2022 - Wiley Online Library
Janus kinase (JAK) inhibitors have become promising treatments for atopic dermatitis (AD),
however no study directly comparing JAK inhibitors with each other has been reported. We …

Two phase 3 trials of lebrikizumab for moderate-to-severe atopic dermatitis

JI Silverberg, E Guttman-Yassky, D Thaçi… - … England Journal of …, 2023 - Mass Medical Soc
Background Lebrikizumab, a high-affinity IgG4 monoclonal antibody targeting interleukin-13,
prevents the formation of the interleukin-4Rα–interleukin-13Rα1 heterodimer receptor …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Global, regional, and national burden of allergic disorders and their risk factors in 204 countries and territories, from 1990 to 2019: A systematic analysis for the Global …

YH Shin, J Hwang, R Kwon, SW Lee, MS Kim… - Allergy, 2023 - Wiley Online Library
Background Asthma and atopic dermatitis (AD) are chronic allergic conditions, along with
allergic rhinitis and food allergy and cause high morbidity and mortality both in children and …

Novel insights into atopic dermatitis

CF Schuler IV, AC Billi, E Maverakis, LC Tsoi… - Journal of Allergy and …, 2023 - Elsevier
Recent research into the pathophysiology and treatment of atopic dermatitis (AD) has shown
notable progress. An increasing number of aspects of the immune system are being …

Multiple roles for cytokines in atopic dermatitis: from pathogenic mediators to endotype-specific biomarkers to therapeutic targets

L Fania, G Moretta, F Antonelli, E Scala… - International Journal of …, 2022 - mdpi.com
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, which
generally presents with intense itching and recurrent eczematous lesions. AD affects up to …

Magnitude and temporal trend of acne vulgaris burden in 204 countries and territories from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019

H Chen, TC Zhang, XL Yin, JY Man… - British Journal of …, 2022 - academic.oup.com
Background Acne vulgaris is widespread across the world. Mapping the latest magnitudes
and temporal trends of acne vulgaris provides the essential foundation for targeted public …

Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells

J Lee, WH Van Der Valk, SA Serdy, CC Deakin, J Kim… - Nature protocols, 2022 - nature.com
Human skin uses millions of hairs and glands distributed across the body surface to function
as an external barrier, thermoregulator and stimuli sensor. The large-scale generation of …

Trends in eczema prevalence in children and adolescents: A Global Asthma Network Phase I Study

SM Langan, AR Mulick, CE Rutter… - Clinical & …, 2023 - Wiley Online Library
Background Eczema (atopic dermatitis) is a major global public health issue with high
prevalence and morbidity. Our goal was to evaluate eczema prevalence over time, using …