Colonic drug delivery can facilitate access to unique therapeutic targets and has the
potential to enhance drug bioavailability whilst reducing off-target effects. Delivering drugs to …

Methanogenic archaea are known as human gut inhabitants since more than 30 years ago
through the detection of methane in the breath and isolation of two methanogenic species …

Highlights•Intestinal microbiota performs diverse metabolic functions essential for host
physiology.•Small molecule products of microbiota metabolism act as nutrients and …

Lotus seed resistant starch, known as resistant starch type 3 (LRS3), was orally
administered to mice to investigate its effects on the gut microbiota, short-chain fatty acids …

We devised a single-batch fermentation system to simulate human colonic microbiota from
fecal samples, enabling the complex mixture of microorganisms to achieve densities of up to …

Methods The in vitro system, Environmental Control System for Intestinal Microbiota, was
used to simulate the environmental conditions of 3 different anatomical parts of the human …

This study presents a computer-controlled dynamic SIMulator of the GastroIntestinal tract,
SIMGI, which was designed to simulate the complete processes of digestion and …

The Twin Simulator of the Human Intestinal Microbial Ecosystem (TWINSHIME®) was
initially developed to study the luminal gut microbiota of the ascending (AC), transverse …

The gut microbiota directly impacts the pathophysiology of different human body districts.
Consequently, microbiota investigation is an hot topic of research and its in vitro culture has …

Benzo [a] pyrene (B [a] P) is a ubiquitous, persistent, and carcinogenic pollutant that belongs
to the large family of polycyclic aromatic hydrocarbons. Population exposure primarily …