Cannabinoids and the expanded endocannabinoid system in neurological disorders

L Cristino, T Bisogno, V Di Marzo - Nature Reviews Neurology, 2020 - nature.com
Anecdotal evidence that cannabis preparations have medical benefits together with the
discovery of the psychotropic plant cannabinoid Δ9-tetrahydrocannabinol (THC) initiated …

Roles of endocannabinoids and endocannabinoid-like molecules in energy homeostasis and metabolic regulation: a nutritional perspective

SMK Rahman, T Uyama, Z Hussain… - Annual Review of …, 2021 - annualreviews.org
The endocannabinoid system is involved in signal transduction in mammals. It comprises
principally G protein-coupled cannabinoid receptors and their endogenous agonists, called …

Oleoylethanolamide supplementation in obese patients newly diagnosed with non-alcoholic fatty liver disease: Effects on metabolic parameters, anthropometric …

H Tutunchi, A Ostadrahimi, M Saghafi-Asl… - Pharmacological …, 2020 - Elsevier
The effects of oleoylethanolamide (OEA) on NAFLD are yet to be examined in human. The
objective of the present study was to examine the effects of OEA supplementation along with …

Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: A novel potential treatment for binge eating disorder

A Romano, MV Micioni Di Bonaventura… - …, 2020 - nature.com
Binge eating disorder (BED) is the most frequent eating disorder, for which current
pharmacotherapies show poor response rates and safety concerns, thus highlighting the …

A systematic review of the effects of oleoylethanolamide, a high‐affinity endogenous ligand of PPAR‐α, on the management and prevention of obesity

H Tutunchi, M Saghafi‐Asl… - Clinical and …, 2020 - Wiley Online Library
Along with an increase in overweight and obesity among all age groups, the development of
efficacious and safe anti‐obesity strategies for patients, as well as health systems, is critical …

Gut microbiota and oleoylethanolamide in the regulation of intestinal homeostasis

C De Filippo, A Costa, MV Becagli… - Frontiers in …, 2023 - frontiersin.org
A vast literature strongly suggests that the endocannabinoid (eCB) system and related
bioactive lipids (the paracannabinoid system) contribute to numerous physiological …

Mediterranean diet and neurodegenerative diseases: the neglected role of nutrition in the modulation of the endocannabinoid system

F Armeli, A Bonucci, E Maggi, A Pinto, R Businaro - Biomolecules, 2021 - mdpi.com
Neurodegenerative disorders are a widespread cause of morbidity and mortality worldwide,
characterized by neuroinflammation, oxidative stress and neuronal depletion. The broad …

Oleoylethanolamide: A novel pharmaceutical agent in the management of obesity‐an updated review

P Laleh, K Yaser, O Alireza - Journal of Cellular Physiology, 2019 - Wiley Online Library
Obesity as a multifactorial disorder has been shown a dramatically growing trend recently.
Besides genetic and environmental factors, dysregulation of the endocannabinoid system …

[HTML][HTML] Oleoylethanolamide supplementation reduces inflammation and oxidative stress in obese people: a clinical trial

L Payahoo, Y Khajebishak, MA Jafarabadi… - Advanced …, 2018 - ncbi.nlm.nih.gov
Purpose: Obesity as a serious public health problem worldwide, results in the incidence of
many chronic diseases. Obesity has been recognized as a chronic low-grade inflammation …

Investigation the effect of oleoylethanolamide supplementation on the abundance of Akkermansia muciniphila bacterium and the dietary intakes in people with obesity …

L Payahoo, Y Khajebishak, MR Alivand… - Appetite, 2019 - Elsevier
Akkermansia muciniphila bacterium is one of the inhabitant gut microbiota involving in the
energy homeostasis and inhibition of the inflammations. The present study was designed to …