Synthetic and medicinal perspective of quinolines as antiviral agents

R Kaur, K Kumar - European Journal of Medicinal Chemistry, 2021 - Elsevier
In current scenario, various heterocycles have come up exhibiting crucial role in various
medicinal agents which are valuable for mankind. Out of diverse range of heterocycle …

Synthetic and medicinal perspective of antileishmanial agents: an overview

S Pawar, MK Kumawat, M Kundu, K Kumar - Journal of Molecular Structure, 2023 - Elsevier
Leishmaniasis is one of the most common neglected tropical diseases (NTD), and is
originated in over 98 countries, affecting about 12 million people every year, which is …

Organocatalytic Formal (3 + 2) Cycloaddition toward Chiral Pyrrolo[1,2-a]indoles via Dynamic Kinetic Resolution of Allene Intermediates

JF Bai, L Zhao, F Wang, F Yan, T Kano… - Organic …, 2020 - ACS Publications
We report the chiral phosphoric acid catalyzed formal (3+ 2) cycloaddition of 3-substituted 1
H-indoles and propargylic alcohols containing a functional directing group (p-NHAc or p …

TosMIC: A powerful synthon for cyclization and sulfonylation

K Kumar - ChemistrySelect, 2020 - Wiley Online Library
Abstract p‐tosylmethyl isocyanide (TosMIC) which is also known as van Leusen's reagent
hold the three functionalized groups including the isocyanide and sulfonyl group and an …

Asymmetric Synthesis of Halocyclized Products by Using Various Catalysts: A State‐of‐the‐Art Review

S De, A Kumar Dan, R Sahu… - European Journal of …, 2022 - Wiley Online Library
Halogens play a crucial part in synthetic organic chemistry. Halo‐cyclized products hold
numerous applications in the pharmaceutical industries, agrochemicals, natural product …

Synthetic and Medicinal Perspective of 1, 2, 4‐Triazole as Anticancer Agents

B Rathod, K Kumar - Chemistry & Biodiversity, 2022 - Wiley Online Library
Cancer is still one of the leading causes of death worldwide. Many researchers are working
to design and develop heterocyclic‐based drugs with the potential to treat cancer at various …

Microwave‐assisted diversified synthesis of pyrimidines: An overview

K Kumar - Journal of Heterocyclic Chemistry, 2022 - Wiley Online Library
Pyrimidines and their hybrid molecules have continued to be a favorable area for organic
chemists owing to their richness in natural and synthetic compounds with multifarious …

Catalytic and Chemodivergent Synthesis of 1-Substituted 9H-Pyrrolo[1,2-a]indoles via Annulation of β-CF3 Enones with 3-Substituted Indoles

H Sindhe, N Saiyed, A Kamble… - The Journal of …, 2022 - ACS Publications
Chemodivergent reactions are more advantageous in organic synthesis that yield diversely
functionalized scaffolds from common starting materials. Herein, we report an efficient metal …

The literature of heterocyclic chemistry, Part XIX, 2019

LI Belen'kii, GA Gazieva, YB Evdokimenkova… - Advances in …, 2022 - Elsevier
A systematized survey of reviews and monographs published in 2019 on all aspects of
heterocyclic chemistry is given. Methods for the synthesis, reactivity, and practically useful …

Synthesis and clinical development of Palbociclib: an overview

D Konar, S Maru, S Kar, K Kumar - Medicinal Chemistry, 2022 - ingentaconnect.com
Breast cancer is the second most commonly identified cancer in women in the United States
after skin cancer. The past few years have seen a substantial increase in breast cancer …