[HTML][HTML] Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

[HTML][HTML] Neurohormetic phytochemicals in the pathogenesis of neurodegenerative diseases

A Sahebnasagh, S Eghbali, F Saghafi, A Sureda… - Immunity & …, 2022 - Springer
The world population is progressively ageing, assuming an enormous social and health
challenge. As the world ages, neurodegenerative diseases are on the rise. Regarding the …

Neuroprotective effects of oleuropein: Recent developments and contemporary research

MS Butt, U Tariq, A Naz… - Journal of Food …, 2021 - Wiley Online Library
Neurological disorders are increasing at a faster pace due to oxidative stress, protein
aggregation, excitotoxicity, and neuroinflammation. It is reported that the Mediterranean diet …

Glutathione peroxidase-1 and neuromodulation: Novel potentials of an old enzyme

G Sharma, EJ Shin, N Sharma, SY Nah, HN Mai… - Food and Chemical …, 2021 - Elsevier
Glutathione peroxidase (GPx) acts in co-ordination with other signaling molecules to exert its
own antioxidant role. We have demonstrated the protective effects of GPx,/GPx-1, a …

Protective effect of olive leaves phenolic compounds against neurodegenerative disorders: Promising alternative for Alzheimer and Parkinson diseases modulation

F Hadrich, M Chamkha, S Sayadi - Food and Chemical Toxicology, 2022 - Elsevier
The main objective of this work was to review literature on compounds extracted from olive
tree leaves, such as simple phenols (hydroxytyrosol) and flavonoids (Apigenin, apigenin-7 …

Melatonin and morphine: potential beneficial effects of co‐use

K Hemati, MH Pourhanifeh… - Fundamental & …, 2021 - Wiley Online Library
Morphine is a potent analgesic agent used to control acute or chronic pain. Chronic
administration of morphine results in analgesic tolerance, hyperalgesia, and other side …

[HTML][HTML] The multiple sclerosis modulatory potential of natural multi-targeting antioxidants

P Theodosis-Nobelos, EA Rekka - Molecules, 2022 - mdpi.com
Multiple sclerosis (MS) is a complex neurodegenerative disease. Although its pathogenesis
is rather vague in some aspects, it is well known to be an inflammatory process …

[HTML][HTML] Carveol mitigates the development of the morphine anti-nociceptive tolerance, physical dependence, and conditioned place preference in mice

I Badshah, NG Qazi, M Anwar, B Shaukat, MI Khan… - Heliyon, 2024 - cell.com
Emergence of analgesic tolerance and dependence to morphine is frequently the limiting
factor in the use of this agent in the management of pain. Hence, this study aimed to …

Insufficient autophagy enables the nuclear factor erythroid 2-related factor 2 (NRF2) to promote ferroptosis in morphine-treated SH-SY5Y cells

X Huang, X Yan, G Chen, Y Feng, Y Bai, P Yan… - …, 2024 - Springer
Rationale While morphine has important therapeutic value it is also one of the most widely
abused drugs in the world. As a newly discovered style of cell death, ferroptosis is involved …

The protective effect of carvacrol and thymol as main polyphenolic compounds of thyme on some biologic systems in disease condition: A narrative review

A Kaeidi, MR Rahmani… - Journal of Rafsanjan …, 2020 - journal.rums.ac.ir
Thyme plant is a member of the mint family that is considered as an aromatic perennial
evergreen medical herb. Carvacrol and thymol are known as two important phenolic …