Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

In the decade since the discovery of the innate immune cyclic GMP–AMP synthase (cGAS)–
2′ 3′-cyclic GMP–AMP (cGAMP)–stimulator of interferon genes (STING) pathway, its …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic, resulting in millions of infections and deaths with few effective interventions …

Coronaviruses are a family of RNA viruses that cause acute and chronic diseases of the
upper and lower respiratory tract in humans and other animals. Severe acute respiratory …

The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

The SARS-CoV-2 papain-like protease (PLpro), which has deubiquitinating activity,
suppresses the type I interferon (IFN-I) antiviral response. We investigated the mechanism …

The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-
equipped for future pandemics. While unprecedented strides have been made developing …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged at the end of
2019 and caused the pandemic of coronavirus disease 2019 (COVID-19). Basic and clinical …

Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular
antiviral response. Despite the growing interest in understanding the interplay between SGs …