An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty
acids and have important roles in orchestrating the resolution of tissue inflammation—that is …

Abstract Prostaglandin E 2 (PGE 2) is a bioactive lipid that elicits a wide range of biological
effects associated with inflammation and cancer. PGE 2 exerts diverse effects on cell …

Acute inflammation normally resolves by mechanisms that have remained somewhat
elusive. Emerging evidence now suggests that an active, coordinated program of resolution …

Neutrophils are the first immune cells recruited to a site of injury or infection, where they
perform many functions. Having completed their role, neutrophils must be removed from the …

Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

This study aims to evaluate the possible mechanisms responsible for the anti-inflammatory
effects of apigenin lipopolysaccharide (LPS)-induced inflammatory in acute lung injury. In …

Acute respiratory distress syndrome (ARDS) represents a significant burden to the
healthcare system, with≈ 200 000 cases diagnosed annually in the USA. ARDS patients …

Acute inflammation in the lung is essential to health. So too is its resolution. In response to
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-associated
mortality in the US. Previously, we established an immune-mediated TRALI mouse model …