Cannabidiol adverse effects and toxicity

MA Huestis, R Solimini, S Pichini… - Current …, 2019 - ingentaconnect.com
Background: Currently, there is a great interest in the potential medical use of cannabidiol
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …

Use of cannabidiol (CBD) for the treatment of chronic pain

I Urits, K Gress, K Charipova, K Habib, D Lee… - Best Practice & …, 2020 - Elsevier
Chronic pain can be recurrent or constant pain that lasts for longer than 3 months and can
result in disability, suffering, and a physical disturbance. Related to the complex nature of …

Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …

D Haspula, MA Clark - International journal of molecular sciences, 2020 - mdpi.com
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

The Genomics of Cannabis and Its Close Relatives

I Kovalchuk, M Pellino, P Rigault… - Annual Review of …, 2020 - annualreviews.org
Cannabis sativa L. is an important yet controversial plant with a long history of recreational,
medicinal, industrial, and agricultural use, and together with its sister genus Humulus, it …

Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa

AR de Mello Schier… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are pathologies that affect human beings in many aspects of life,
including social life, productivity and health. Cannabidiol (CBD) is a constituent non …

Potential and limits of cannabinoids in Alzheimer's disease therapy

G Abate, D Uberti, S Tambaro - Biology, 2021 - mdpi.com
Simple Summary This review was aimed at exploring the potentiality of drugging the
endocannabinoid system as a therapeutic option for Alzheimer's disease (AD). Recent …

The efficacy of cannabis on multiple sclerosis-related symptoms

F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in
the central nervous system. MS is characterized by its most common symptoms of spasticity …

An individuality of response to cannabinoids: challenges in safety and efficacy of cannabis products

S Kitdumrongthum, D Trachootham - Molecules, 2023 - mdpi.com
Since legalization, cannabis/marijuana has been gaining considerable attention as a
functional ingredient in food.∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other …

Use of cannabidiol for the treatment of anxiety: a short synthesis of pre-clinical and clinical evidence

M Wright, P Di Ciano, B Brands - Cannabis and cannabinoid …, 2020 - liebertpub.com
Anxiety disorders have the highest lifetime prevalence of any mental illness worldwide,
leading to high societal costs and economic burden. Current pharmacotherapies for anxiety …