RAGE inhibitors for targeted therapy of cancer: a comprehensive review
The receptor for advanced glycation end products (RAGE) is a member of the
immunoglobulin family that is overexpressed in several cancers. RAGE is highly expressed …
immunoglobulin family that is overexpressed in several cancers. RAGE is highly expressed …
An update on S100A16 in human cancer
S Basnet, EM Vallenari, U Maharjan, S Sharma… - Biomolecules, 2023 - mdpi.com
S100A16 is a member of the S100 protein family. S100A16 is expressed in a variety of
human tissues, although at varying levels. S100A16 expression is especially high in tissues …
human tissues, although at varying levels. S100A16 expression is especially high in tissues …
Brain microvascular endothelial cell exosome–mediated S100A16 up‐regulation confers small‐cell lung cancer cell survival in brain
ZH Xu, ZW Miao, QZ Jiang, DX Gan, XG Wei… - The FASEB …, 2019 - Wiley Online Library
Small cell lung cancer (SCLC) is the most aggressive histologic subtype of lung cancer, with
a strong predilection for early brain metastases. Despite efforts and advances in new …
a strong predilection for early brain metastases. Despite efforts and advances in new …
[HTML][HTML] S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway
S Ou, Y Liao, J Shi, J Tang, Y Ye… - Molecular …, 2021 - spandidos-publications.com
S100 calcium binding protein A16 (S100A16) is the most recent member of the S100
calcium-binding protein family. The function of S100A16 has been associated with various …
calcium-binding protein family. The function of S100A16 has been associated with various …
S100A16 induces epithelial-mesenchymal transition in human PDAC cells and is a new therapeutic target for pancreatic cancer treatment that synergizes with …
T Li, T Ren, C Huang, Y Li, P Yang, G Che, L Luo… - Biochemical …, 2021 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with a poor 5-
year survival rate of approximately 6%, mostly due to poor treatment response and early …
year survival rate of approximately 6%, mostly due to poor treatment response and early …
An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16
L Ma, G Li, T Yang, L Zhang, X Wang, X Xu… - Cancer Chemotherapy …, 2022 - Springer
Abstract Purpose Among children, glioblastomas (GBMs) are a relatively common type of
brain tumor. BRD4 expression was elevated in GBM and negatively correlated with the …
brain tumor. BRD4 expression was elevated in GBM and negatively correlated with the …
A Novel Immune‐Related Prognostic Signature Predicting Survival in Patients with Pancreatic Adenocarcinoma
X Zhang, X Li, J Xie, Q Zhu, Y Yuan - Journal of Oncology, 2022 - Wiley Online Library
Pancreatic adenocarcinoma (PAAD) carries the lowest survival rate of all major organ
cancers, which is of dismal prognosis and high mortality rate. Thus, the present study …
cancers, which is of dismal prognosis and high mortality rate. Thus, the present study …
Novel genome-wide DNA methylation profiling reveals distinct epigenetic landscape, prognostic model and cellular composition of early-stage lung adenocarcinoma
J Gan, M Huang, W Wang, G Fu, M Hu, H Zhong… - Journal of Translational …, 2024 - Springer
Background Lung adenocarcinoma (LUAD) has been a leading cause of cancer-related
mortality worldwide. Early intervention can significantly improve prognosis. DNA methylation …
mortality worldwide. Early intervention can significantly improve prognosis. DNA methylation …
Clinicopathological and prognostic significance of nuclear UGDH localization in lung adenocarcinoma
D Hagiuda, R Nagashio, M Ichinoe, B Tsuchiya… - Biomedical …, 2019 - jstage.jst.go.jp
This study aimed to clarify relationships among UDP-glucose-6 dehydrogenase (UGDH)
expression, clinicopathological factors, and the prognosis of patients, and to determine the …
expression, clinicopathological factors, and the prognosis of patients, and to determine the …
[HTML][HTML] Integrated analysis identifies S100A16 as a potential prognostic marker for pancreatic cancer
T Chen, DM Xia, C Qian, SR Liu - American Journal of …, 2021 - ncbi.nlm.nih.gov
Background: The new S100 protein family member S100A16 is functionally expressed in
various cancers. This study explored the prognostic value and potential role of S100A16 in …
various cancers. This study explored the prognostic value and potential role of S100A16 in …