Catecholaminergic systems in stress: structural and molecular genetic approaches

R Kvetnansky, EL Sabban… - Physiological …, 2009 - journals.physiology.org
Stressful stimuli evoke complex endocrine, autonomic, and behavioral responses that are
extremely variable and specific depending on the type and nature of the stressors. We first …

Catecholamine biosynthesis and physiological regulation in neuroendocrine cells

Flatmark - Acta Physiologica Scandinavica, 2000 - Wiley Online Library
The catecholamines are widely distributed in mammals and their levels and physiological
functions are regulated at many sites. These include their release from neuroendocrine …

Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain

K Sakurada, M Ohshima-Sakurada, TD Palmer… - …, 1999 - journals.biologists.com
Adult rat-derived hippocampal progenitor cells express many of the molecules implicated in
midbrain dopaminergic determination, including FGF receptors 1, 2 and 3, the sonic …

Dopaminergic differentiation of human embryonic stem cells

X Zeng, J Cai, J Chen, Y Luo, ZB You, E Fotter… - Stem …, 2004 - academic.oup.com
In this manuscript we report that human embryonic stem cells (hESCs) differentiated into
dopaminergic neurons when cocultured with PA6 cells. After 3 weeks of differentiation …

Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development

N Matsushita, H Okada, Y Yasoshima… - Journal of …, 2002 - Wiley Online Library
Dopamine (DA)‐producing neurons in the ventral midbrain are generated from a specified
neuronal lineage and form selective axonal pathways that mediate multiple CNS functions …

[HTML][HTML] Identification of a population of peripheral sensory neurons that regulates blood pressure

C Morelli, L Castaldi, SJ Brown, LL Streich… - Cell reports, 2021 - cell.com
The vasculature is innervated by a network of peripheral afferents that sense and regulate
blood flow. Here, we describe a system of non-peptidergic sensory neurons with cell bodies …

Repeated cannabinoid administration increases indices of noradrenergic activity in rats

ME Page, VC Oropeza, SE Sparks, Y Qian… - Pharmacology …, 2007 - Elsevier
The present study examined the impact of repeated administration of a synthetic
cannabinoid agonist, WIN 55,212-2 on the coeruleo-cortical pathway, a circuit implicated in …

A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter

P Cazorla, MP Smidt, KL O'Malley… - Journal of …, 2000 - Wiley Online Library
Tyrosine hydroxylase (TH) is the rate‐limiting enzyme in the biosynthesis of catecholamines,
which takes place in different types of neuronal systems and nonneuronal tissues. The …

Phenotypic differentiation during migration of dopaminergic progenitor cells to the olfactory bulb

H Baker, N Liu, HS Chun, S Saino… - Journal of …, 2001 - Soc Neuroscience
A possible source for transplantable neurons in Parkinson's disease are adult olfactory bulb
(OB) dopamine (DA) progenitors that originate in the anterior subventricular zone and reach …

Pitx3 activates mouse tyrosine hydroxylase promoter via a high‐affinity binding site

M Lebel, Y Gauthier, A Moreau… - Journal of …, 2001 - Wiley Online Library
Tyrosine hydroxylase (TH) is the rate‐limiting enzyme of dopamine and (nor) adrenaline
biosynthesis. Regulation of its gene expression is complex and different regulatory …