Abstract The versatility of Artificial Intelligence (AI) in process systems is not restricted to
modelling and control only, but also as estimators to estimate the unmeasured parameters …

In this chapter, different approaches for open-loop and closed-loop control applied in
bioprocess automation are discussed. Although in recent years many contributions dealing …

The exploitation of dynamic process conditions increasingly finds attention for strain
screening and bioprocess development of biotechnological products. Prerequisite for …

Protein solubility plays a critical role in improving production yield of recombinant proteins in
biocatalysis applications. To some extent, protein solubility can represent the function and …

In this work a feedforward neural network, trained and validated using experimental values
of freezing and thawing times of foods and test substances of different geometries, is …

This paper provides a perspective on the increasingly critical role that systems analysis and
process control play in bioprocess development today. This is of particular importance to the …

In this paper, a robust super-twisting sliding mode control with adaptive tuning law is
developed for a nonlinear biotechnological process, which takes place inside a continuous …

Due to growing worldwide energy demand, the search for diversification of the energy matrix
stands out as an important research topic. Bioethanol represents a notable alternative of …

Bioreactors (fermenters) are the key unit operation in biopharmaceutical, brewing,
biochemical, biofuel, and waste treatment processes. The need for monitoring, control, and …

A tight and robust yeast fermentation controller is usually difficult to achieve because of the
inherent uncertainty, nonlinear, and time-varying characteristics of the yeast fermentation …