[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

[HTML][HTML] Neuroprotective action of resveratrol

S Bastianetto, C Ménard, R Quirion - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Low-to-moderate red wine consumption appeared to reduce age-related neurological
disorders including macular degeneration, stroke, and cognitive deficits with or without …

Resveratrol-selenium nanoparticles alleviate neuroinflammation and neurotoxicity in a rat model of Alzheimer's disease by regulating Sirt1/miRNA-134/GSK3β …

OAR Abozaid, MW Sallam, S El-Sonbaty… - … Trace Element Research, 2022 - Springer
Alzheimer's disease (AD) is a brain disorder associated with a gradual weakening in
neurocognitive functions, neuroinflammation, and impaired signaling pathways. Resveratrol …

Resveratrol and neuroprotection: impact and its therapeutic potential in Alzheimer's disease

MH Rahman, R Akter, T Bhattacharya… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a progressive cortex and hippocampal neurodegenerative
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

R Hardeland, JA Madrid, DX Tan… - Journal of pineal …, 2012 - Wiley Online Library
Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …

Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease

Y Wu, X Li, JX Zhu, W Xie, W Le, Z Fan, J Jankovic… - Neurosignals, 2011 - karger.com
Excessive misfolded proteins and/or dysfunctional mitochondria, which may cause energy
deficiency, have been implicated in the etiopathogenesis of Parkinson's disease (PD) …

Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms

R Hardeland - Journal of pineal research, 2013 - Wiley Online Library
The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …

Mechanisms of melatonin in alleviating Alzheimer's disease

M Shukla, P Govitrapong, P Boontem… - Current …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

Resveratrol derivatives as potential treatments for Alzheimer's and Parkinson's disease

BD Arbo, C André-Miral, RG Nasre-Nasser… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

The neuroprotective effect of Klotho is mediated via regulation of members of the redox system

E Zeldich, CD Chen, TA Colvin… - Journal of Biological …, 2014 - ASBMB
Generation of reactive oxygen species (ROS), leading to oxidative damage and neuronal
cell death, plays an important role in the pathogenesis of neurodegenerative disorders …