Computational protein structure refinement: almost there, yet still so far to go

M Feig - Wiley Interdisciplinary Reviews: Computational …, 2017 - Wiley Online Library
Protein structures are essential in modern biology yet experimental methods are far from
being able to catch up with the rapid increase in available genomic data. Computational …

Methods for the refinement of protein structure 3D models

R Adiyaman, LJ McGuffin - International journal of molecular sciences, 2019 - mdpi.com
The refinement of predicted 3D protein models is crucial in bringing them closer towards
experimental accuracy for further computational studies. Refinement approaches can be …

3Drefine: an interactive web server for efficient protein structure refinement

D Bhattacharya, J Nowotny, R Cao… - Nucleic acids …, 2016 - academic.oup.com
Abstract 3Drefine is an interactive web server for consistent and computationally efficient
protein structure refinement with the capability to perform web-based statistical and visual …

Design of a multi-epitope vaccine against SARS-CoV-2 using immunoinformatics approach

S Sanami, M Zandi, B Pourhossein, GR Mobini… - International journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused COVID-19 disease
in China. So far, no vaccine has licensed to protect against infection with COVID-19 …

3Drefine: Consistent protein structure refinement by optimizing hydrogen bonding network and atomic‐level energy minimization

D Bhattacharya, J Cheng - Proteins: Structure, Function, and …, 2013 - Wiley Online Library
One of the major limitations of computational protein structure prediction is the deviation of
predicted models from their experimentally derived true, native structures. The limitations …

Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter

E Ohana, E Hoch, C Keasar, T Kambe, O Yifrach… - Journal of Biological …, 2009 - ASBMB
Vesicular zinc transporters (ZnTs) play a critical role in regulating Zn 2+ homeostasis in
various cellular compartments and are linked to major diseases ranging from Alzheimer …

KoBaMIN: a knowledge-based minimization web server for protein structure refinement

JP Rodrigues, M Levitt, G Chopra - Nucleic acids research, 2012 - academic.oup.com
The KoBaMIN web server provides an online interface to a simple, consistent and
computationally efficient protein structure refinement protocol based on minimization of a …

Automated server predictions in CASP7

JND Battey, J Kopp, L Bordoli, RJ Read… - Proteins: Structure …, 2007 - Wiley Online Library
With each round of CASP (Critical Assessment of Techniques for Protein Structure
Prediction), automated prediction servers have played an increasingly important role. Today …

BALL-biochemical algorithms library 1.3

A Hildebrandt, AK Dehof, A Rurainski, A Bertsch… - BMC …, 2010 - Springer
Abstract Background The Biochemical Algorithms Library (BALL) is a comprehensive rapid
application development framework for structural bioinformatics. It provides an extensive …

QDeep: distance-based protein model quality estimation by residue-level ensemble error classifications using stacked deep residual neural networks

MH Shuvo, S Bhattacharya, D Bhattacharya - Bioinformatics, 2020 - academic.oup.com
Motivation Protein model quality estimation, in many ways, informs protein structure
prediction. Despite their tight coupling, existing model quality estimation methods do not …