[HTML][HTML] Measuring the microbiome: Best practices for developing and benchmarking microbiomics methods

NA Bokulich, M Ziemski, MS Robeson II… - Computational and …, 2020 - Elsevier
Microbiomes are integral components of diverse ecosystems, and increasingly recognized
for their roles in the health of humans, animals, plants, and other hosts. Given their …

Intestinal organoids: a tool for modelling diet–microbiome–host interactions

J Rubert, PJ Schweiger, F Mattivi, K Tuohy… - Trends in Endocrinology …, 2020 - cell.com
Dietary patterns, microbiome dysbiosis, and gut microbial metabolites (GMMs) have a
pivotal role in the homeostasis of intestinal epithelial cells and in disease progression, such …

Gut microbiota of Chinese obese children and adolescents with and without insulin resistance

X Yuan, R Chen, Y Zhang, X Lin, X Yang… - Frontiers in …, 2021 - frontiersin.org
Objective The intestinal flora of gut microbiota in obese Chinese children and adolescents
with and without insulin resistance (IR) was analyzed, as well as associations between the …

[HTML][HTML] Gut microbiota diversity in middle-aged and elderly patients with end-stage diabetic kidney disease

R Chen, D Zhu, R Yang, Z Wu, N Xu… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Diabetic kidney disease (DKD) is the most common cause of end-stage renal
disease (ESRD), but the mechanism between DKD and ESRD remains unclear. Some …

Zucker Diabetic‐Sprague Dawley (ZDSD) rat: type 2 diabetes translational research model

AN Wang, J Carlos, GM Fraser… - Experimental …, 2022 - Wiley Online Library
New Findings What is the topic of this review? The Zucker Diabetic‐Sprague Dawley
(ZDSD) rat is in the early adoption phase of use by researchers in the fields of diabetes …

Microbial taxonomic and functional shifts in adolescents with type 1 diabetes are associated with clinical and dietary factors

P Mokhtari, P Jambal, JM Metos, K Shankar… - …, 2023 - thelancet.com
Background Evidence indicates a link between the pathogenesis of type 1 diabetes (T1D)
and the gut microbiome. However, the regulation of microbial metabolic pathways and the …

Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention

D Grapov, O Fiehn, C Campbell… - American Journal …, 2019 - journals.physiology.org
Insulin resistance has wide-ranging effects on metabolism, but there are knowledge gaps
regarding the tissue origins of systemic metabolite patterns and how patterns are altered by …

Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites

KE Mercer, L Yeruva, L Pack… - American Journal …, 2020 - journals.physiology.org
The gut microbiome has the potential to create or modify xenometabolites (ie, nonhost-
derived metabolites) through de novo synthesis or modification of exogenous and …

Single-anastomosis duodenal jejunal bypass improve glucose metabolism by regulating gut microbiota and short-chain fatty acids in Goto-Kakisaki rats

X Yu, Z Wu, Z Song, H Zhang, J Zhan, H Yu… - Frontiers in …, 2020 - frontiersin.org
In recent years, bariatric surgery has emerged as a promising treatment for type 2 diabetes.
Bariatric surgery is known to cause alterations in the relative abundance and composition of …

Progression of diabetes is associated with changes in the ileal transcriptome and ileal‐colon morphology in the UC Davis Type 2 Diabetes Mellitus rat

BD Piccolo, JL Graham, P Kang… - Physiological …, 2021 - Wiley Online Library
Deterioration in glucose homeostasis has been associated with intestinal dysbiosis, but it is
not known how metabolic dysregulation alters the gastrointestinal environment. We …