Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

18F-Fluorination of Nitroimidazolyl-Containing Sultone: A Direct Access to a Highly Hydrophilic Radiotracer for High-Performance Positron Emission Tomography …

C Maingueneau, AE Lafargue, S Guillouet, F Fillesoye… - JACS Au, 2024 - ACS Publications
Hypoxia, characterized by nonphysiological levels of oxygen tension, is a key phenomenon
common to the majority of malignant tumors with poor prognosis. Many efforts have been …

Synthesis and Preclinical Evaluation of Two Novel 68Ga-Labeled Bispecific PSMA/FAP-Targeted Tracers with 2-Nal-Containing PSMA-Targeted Pharmacophore and …

A Verena, H Merkens, CC Chen, DE Chapple, L Wang… - Molecules, 2024 - mdpi.com
Some bispecific radiotracers have been developed to overcome the limitations of
monospecific tracers and improve detection sensitivity for heterogeneous tumor lesions …

Preparation and bioevaluation of a novel 99mTc-labelled propylene amine oxime (PnAO) containing two 4-methyl-2-nitroimidazole groups as a promising tumor …

S Li, T Chu - Bioorganic & Medicinal Chemistry Letters, 2024 - Elsevier
Hypoxia is a common phenomenon in solid tumors, and its presence inhibits the efficacy of
tumor chemotherapy and radiotherapy. Accurate measurement of hypoxia before tumor …

A thiourea‐bridged 99mTc(CO)3‐dipicolylamine‐2‐nitroimidazole complex for targeting tumor hypoxia: Utilizing metabolizable thiourea‐bridge to improve …

S Mittal, C Kumar, L Jha… - Drug Development …, 2024 - Wiley Online Library
Abstract The 2‐nitroimidazole based 99mTc‐radiopharmaceuticals are widely explored for
imaging tumor hypoxia. Radiopharmaceuticals for targeting hypoxia are often lipophilic and …

Insights in PET and SPECT: 2023

M Petretta, C Nappi, A Cuocolo - Frontiers in Nuclear Medicine, 2023 - frontiersin.org
It is a pleasure and an honor for us to introduce the Research Topic Insights in PET and
SPECT: 2023, published in the PET and SPECT section of Frontiers in Nuclear Medicine …