Etiology of severe community-acquired pneumonia in adults based on metagenomic next-generation sequencing: a prospective multicenter study

X Wu, Y Li, M Zhang, M Li, R Zhang, X Lu… - Infectious Diseases and …, 2020 - Springer
Background Metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage
fluid (BALF) has the potential to improve the pathogen identification in severe community …

Defining lower airway bacterial infection in children with chronic endobronchial disorders

KM Hare, SJ Pizzutto, AB Chang… - Pediatric …, 2018 - Wiley Online Library
Background Differentiating lower airway bacterial infection from possible upper airway
contamination in children with endobronchial disorders undergoing bronchoalveolar lavage …

Broad range detection of viral and bacterial pathogens in bronchoalveolar lavage fluid of children to identify the cause of lower respiratory tract infections

H Wang, J Gu, X Li, CE van der Gaast-de Jongh… - BMC infectious …, 2021 - Springer
Background Knowledge on the etiology of LRTIs is essential for improvement of the clinical
diagnosis and accurate treatment. Molecular detection methods were applied to identify a …

Risk factors and incidence of invasive bacterial infection in severe bronchiolitis: the RICOIB prospective study

C Guitart, C Alejandre, S Bobillo-Perez… - BMC pediatrics, 2022 - Springer
Background Bacterial infection (BI), both community-acquired (CA-BI) and hospital-acquired
(HAI), might present as a severe complication in patients with bronchiolitis. This study aimed …

Inhibition of the PI3K/AKT Signaling Pathway or Overexpression of Beclin1 Blocks Reinfection of Streptococcus pneumoniae After Infection of Influenza A Virus in …

Z Yang, X Zou, P Feng, H Zhan, D Xiong, J Lang - Inflammation, 2019 - Springer
Streptococcus pneumoniae (S. pneumoniae) and viruses are considered as primary risks of
community-acquired pneumonia (CAP), and the effects of co-infection bacterial and virus in …

Emerging pneumonia and acute lower respiratory infections in children, volume II

HR Yu, JH Hsu - Frontiers in Pediatrics, 2024 - frontiersin.org
leading to what is known as" immunological debt"(3). Given the changes in the era and
environment and the advancements in science, management strategies for childhood …

Arsenic alters transcriptional responses to Pseudomonas aeruginosa infection and decreases antimicrobial defense of human airway epithelial cells

BC Goodale, EJ Rayack, BA Stanton - Toxicology and applied …, 2017 - Elsevier
Arsenic contamination of drinking water and food threatens the health of hundreds of
millions of people worldwide by increasing the risk of numerous diseases. Arsenic exposure …

[HTML][HTML] 纤维支气管镜检查行支气管肺泡灌洗术在儿童慢性肺炎中的诊断与应用价值

吴会芳, 张景丽, 刘晓娟, 刘新锋, 张中平… - 河北医科大学 …, 2021 - xuebao.hebmu.edu.cn
目的探讨纤维支气管镜检查(fiberoptic bronchoscopy, BFS) 行支气管肺泡灌洗术(
bronchoalveolar lavage, BAL) 在儿童慢性肺炎诊断及治疗中的应用价值 …

纤维支气管镜用于儿童肺部感染性疾病诊治进展

王丽君, 徐姗姗, 李华君 - 临床儿科杂志, 2020 - jcp.xinhuamed.com.cn
For more than 40 years, fiberoptic bronchoscopy has been widely used in the diagnosis and
treatment of children's lung diseases. With the development of clinical research and the …

Childhood pneumonia diagnostics: a narrative review

O Ojuawo, A Ojuawo, A Aladesanmi… - Expert Review of …, 2022 - Taylor & Francis
Background Childhood pneumonia remains the leading infectious cause of death in children
with highest mortality figures in sub-Saharan Africa and Southeast Asia. The primary …