For nearly a century, the diagnosis and grading of oligodendrogliomas and
oligoastrocytomas has been based on histopathology alone. Roughly 20 years ago, the first …

The term long‐term epilepsy associated tumor (LEAT) encompasses lesions identified in
patients investigated for long histories (often 2 years or more) of drug‐resistant epilepsy …

Rare, generally pediatric oligodendroglioma-like neoplasms with extensive leptomeningeal
dissemination have been interpreted variably as glial, oligodendroglial or glioneuronal. The …

Neoplasms of the central nervous system (CNS) are the most frequently encountered solid
tumors of childhood, but are less common in adolescents and young adults (AYA), aged 15 …

Context.—Significant interobserver variability exists with respect to the diagnosis of
oligodendroglial neoplasms, especially their distinction from astrocytoma and mixed …

Abstract Isocitrate dehydrogenase 1 (IDH1) mutations are frequent in astrocytomas,
oligoastrocytomas and oligodendrogliomas. We previously reported the generation of a …

Despite advances in therapy, gliomas remain associated with poor prognosis. Clinical
advances will be achieved through molecularly targeted biological therapies, for which …

The peculiar radiological and pathological findings of four pediatric cases admitted to the
University Hospital of Padua between 1990 and 2007 are described. In all cases, the …

Fluorescence in situ hybridization (FISH) is a powerful, morphology‐based technique to
assess targeted copy number alterations or gene rearrangements in formalin‐fixed, paraffin …

Low-grade gliomas represent the most frequent brain tumors arising during childhood. They
are characterized by a broad and heterogeneous group of tumors that are currently …