Saffron (Crocus sativus L.), the king of spices: An overview

L Cardone, D Castronuovo, M Perniola, N Cicco… - Scientia …, 2020 - Elsevier
Saffron is obtained from the dried red stigmas of Crocus sativus L., an autumnal herbaceous
flowering plant belonging to the Iridaceae family. It is largely cultivated in Iran, India …

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer's disease: The role of antioxidants in prevention and …

G Juszczyk, J Mikulska, K Kasperek, D Pietrzak… - Antioxidants, 2021 - mdpi.com
There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …

Neuroprotective herbs for the management of Alzheimer's disease

J Gregory, YV Vengalasetti, DE Bredesen, RV Rao - Biomolecules, 2021 - mdpi.com
Background—Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative
disease that is characterized by memory loss, personality changes, and a decline in …

Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

β-Amyloid: the key peptide in the pathogenesis of Alzheimer's disease

X Sun, WD Chen, YD Wang - Frontiers in pharmacology, 2015 - frontiersin.org
The amyloid β peptide (Aβ) is a critical initiator that triggers the progression of Alzheimer's
Disease (AD) via accumulation and aggregation, of which the process may be caused by Aβ …

Bioactivity assessment and toxicity of crocin: a comprehensive review

SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …

Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Traditional and Modern Uses of Saffron (Crocus Sativus)

I Mzabri, M Addi, A Berrichi - Cosmetics, 2019 - mdpi.com
The Aromatic and Medicinal Plants sector has undergone a remarkable evolution, especially
during the last decade. The global market is moving more and more towards products of …

Phytochemistry, pharmacology, and potential clinical applications of saffron: A review

B Xing, S Li, J Yang, D Lin, Y Feng, J Lu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Saffron, the dried red stigma of the perennial herb Crocus
sativus L.(Iridaceae), is one of the most important and expensive spices in the world. It is …