Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

The Morris water maze (MWM) was described 20 years ago as a device to investigate
spatial learning and memory in laboratory rats. In the meanwhile, it has become one of the …

Metastatic seeding by disseminated cancer cells principally occurs in perivascular niches.
Here, we show that mechanotransduction signalling triggered by the pericyte-like spreading …

Background: Although limited environmental exploration in autism is an obvious behavioral
feature and may be a manifestation of “restricted interests” as described in DSM-IV criteria …

The broad variation in phenotypes and severities within autism spectrum disorders suggests
the involvement of multiple predisposing factors, interacting in complex ways with normal …

Most cells are part of multicellular structures or tissues within the body. In epithelia, the cells
are closely linked with each other, whereas in connective tissues the cells are loosely …

Abstract Purpose of Review Hereditary spastic paraplegias are a genetically heterogeneous
group of neurological disorders. Patients present lower limb weakness and spasticity …

Poly-α2, 8-sialic acid (polySia) is a unique modification of the neural cell adhesion molecule,
NCAM, tightly associated with neural development and plasticity. However, the vital role …

Human single gene disorders that affect the nervous system provide a host of natural
mutations that can be deployed in the quest to understand its development and function. A …

In humans, mutations in the L1 cell adhesion molecule are associated with a neurological
syndrome termed CRASH, which includes corpus callosum agenesis, mental retardation …