AIE-based luminescence probes for metal ion detection
The past two decades have witnessed significant advances in the field of aggregation-
induced emission (AIE). Luminescent materials with AIE characteristics (AIEgens) are of …
induced emission (AIE). Luminescent materials with AIE characteristics (AIEgens) are of …
MicroRNAs in development and disease
D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
To identify genetic variation underlying atrial fibrillation, the most common cardiac
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming
Ageing is the gradual decline in organismal fitness that occurs over time leading to tissue
dysfunction and disease. At the cellular level, ageing is associated with reduced function …
dysfunction and disease. At the cellular level, ageing is associated with reduced function …
Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)
DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …
[HTML][HTML] Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2
Y Zhao, JF Ransom, A Li, V Vedantham, M von Drehle… - Cell, 2007 - cell.com
MicroRNAs (miRNAs) are genomically encoded small RNAs used by organisms to regulate
the expression of proteins generated from messenger RNA transcripts. The in vivo …
the expression of proteins generated from messenger RNA transcripts. The in vivo …
The formation and function of the cardiac conduction system
JH van Weerd, VM Christoffels - Development, 2016 - journals.biologists.com
The cardiac conduction system (CCS) consists of distinctive components that initiate and
conduct the electrical impulse required for the coordinated contraction of the cardiac …
conduct the electrical impulse required for the coordinated contraction of the cardiac …
Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation
Rhythmic and effective cardiac contraction depends on appropriately timed generation and
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …
Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac …
Background—Cardiac ion channelopathies are responsible for an ever-increasing number
and diversity of familial cardiac arrhythmia syndromes. We describe a new clinical entity that …
and diversity of familial cardiac arrhythmia syndromes. We describe a new clinical entity that …
[HTML][HTML] Making or breaking the heart: from lineage determination to morphogenesis
D Srivastava - Cell, 2006 - cell.com
The cues governing cardiac cell-fate decisions, cardiac differentiation, and three-
dimensional morphogenesis are rapidly being elucidated. Several themes are emerging that …
dimensional morphogenesis are rapidly being elucidated. Several themes are emerging that …