AIE-based luminescence probes for metal ion detection

P Alam, NLC Leung, J Zhang, RTK Kwok… - Coordination Chemistry …, 2021 - Elsevier
The past two decades have witnessed significant advances in the field of aggregation-
induced emission (AIE). Luminescent materials with AIE characteristics (AIEgens) are of …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

JB Nielsen, RB Thorolfsdottir, LG Fritsche, W Zhou… - Nature …, 2018 - nature.com
To identify genetic variation underlying atrial fibrillation, the most common cardiac
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …

Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

D Gill, A Parry, F Santos, H Okkenhaug, CD Todd… - Elife, 2022 - elifesciences.org
Ageing is the gradual decline in organismal fitness that occurs over time leading to tissue
dysfunction and disease. At the cellular level, ageing is associated with reduced function …

Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)

DA Chistiakov, AN Orekhov, YV Bobryshev - Journal of molecular and …, 2016 - Elsevier
Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …

[HTML][HTML] Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2

Y Zhao, JF Ransom, A Li, V Vedantham, M von Drehle… - Cell, 2007 - cell.com
MicroRNAs (miRNAs) are genomically encoded small RNAs used by organisms to regulate
the expression of proteins generated from messenger RNA transcripts. The in vivo …

The formation and function of the cardiac conduction system

JH van Weerd, VM Christoffels - Development, 2016 - journals.biologists.com
The cardiac conduction system (CCS) consists of distinctive components that initiate and
conduct the electrical impulse required for the coordinated contraction of the cardiac …

Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation

S Nattel, A Maguy, S Le Bouter… - Physiological …, 2007 - journals.physiology.org
Rhythmic and effective cardiac contraction depends on appropriately timed generation and
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac …

C Antzelevitch, GD Pollevick, JM Cordeiro, O Casis… - Circulation, 2007 - Am Heart Assoc
Background—Cardiac ion channelopathies are responsible for an ever-increasing number
and diversity of familial cardiac arrhythmia syndromes. We describe a new clinical entity that …

[HTML][HTML] Making or breaking the heart: from lineage determination to morphogenesis

D Srivastava - Cell, 2006 - cell.com
The cues governing cardiac cell-fate decisions, cardiac differentiation, and three-
dimensional morphogenesis are rapidly being elucidated. Several themes are emerging that …