Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology

LGN de Almeida, H Thode, Y Eslambolchi… - Pharmacological …, 2022 - ASPET
The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

[HTML][HTML] Oxidative stress, free radicals and antioxidants: Potential crosstalk in the pathophysiology of human diseases

P Chaudhary, P Janmeda, AO Docea… - Frontiers in …, 2023 - frontiersin.org
Introduction: Free radicals are reactive oxygen species that constantly circulate through the
body and occur as a side effect of many reactions that take place in the human body. Under …

[HTML][HTML] Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

[HTML][HTML] Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review

R Abbasi, G Shineh, M Mobaraki, S Doughty… - Journal of Nanoparticle …, 2023 - Springer
Rapidly growing interest in using nanoparticles (NPs) for biomedical applications has
increased concerns about their safety and toxicity. In comparison with bulk materials, NPs …

[HTML][HTML] Response mechanism of plants to drought stress

X Yang, M Lu, Y Wang, Y Wang, Z Liu, S Chen - Horticulturae, 2021 - mdpi.com
With the global climate anomalies and the destruction of ecological balance, the water
shortage has become a serious ecological problem facing all mankind, and drought has …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

[HTML][HTML] Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2022 - mdpi.com
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …

Antioxidants and antioxidant methods: An updated overview

İ Gulcin - Archives of toxicology, 2020 - Springer
Antioxidants had a growing interest owing to their protective roles in food and
pharmaceutical products against oxidative deterioration and in the body and against …

Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …