Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years

YC Tan, C Lahiri - Frontiers in Immunology, 2022 - frontiersin.org
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …

Computational analysis of protein interaction networks for infectious diseases

A Pan, C Lahiri, A Rajendiran… - Briefings in …, 2016 - academic.oup.com
Infectious diseases caused by pathogens, including viruses, bacteria and parasites, pose a
serious threat to human health worldwide. Frequent changes in the pattern of infection …

Interactions between the AraC/XylS-like transcriptional activator InvF of Salmonella Typhimurium, the RNA polymerase alpha subunit and the chaperone SicA

D Cortés-Avalos, A Borges Farias… - Scientific Reports, 2024 - nature.com
Salmonella enterica serovar Typhimurium causes gastroenteritis and systemic infections in
humans. For this bacterium the expression of a type III secretion system (T3SS) and effector …

[HTML][HTML] Rapid and sensitive detection of Salmonella in chickens using loop-mediated isothermal amplification combined with a lateral flow dipstick

ZK Liu, QY Zhang, NN Yang, MG Xu, JF Xu, ML Jing… - 2019 - jmb.or.kr
Salmonellosis is a highly contagious bacterial disease that threatens both human and
poultry health. Tests that can detect Salmonella in the field are urgently required to facilitate …

Identification of key regulatory genes connected to NF-κB family of proteins in visceral adipose tissues using gene expression and weighted protein interaction …

JSM Sabir, A El Omri, NA Shaik, B Banaganapalli… - PLoS …, 2019 - journals.plos.org
Obesity is connected to the activation of chronic inflammatory pathways in both adipocytes
and macrophages located in adipose tissues. The nuclear factor (NF)-κB is a central …

In silico Identification of the Indispensable Quorum Sensing Proteins of Multidrug Resistant Proteus mirabilis

S Pawar, MI Ashraf, S Mujawar, R Mishra… - Frontiers in cellular and …, 2018 - frontiersin.org
Catheter-associated urinary tract infections (CAUTI) is an alarming hospital based disease
with the increase of multidrug resistance (MDR) strains of Proteus mirabilis. Cases of long …

Delineating the Plausible Molecular Vaccine Candidates and Drug Targets of Multidrug-Resistant Acinetobacter baumannii

S Mujawar, R Mishra, S Pawar, D Gatherer… - Frontiers in cellular and …, 2019 - frontiersin.org
Nosocomial infections have become alarming with the increase of multidrug-resistant
bacterial strains of Acinetobacter baumannii. Being the causative agent in~ 80% of the …

The Salmonella Typhimurium InvF-SicA complex is necessary for the transcription of sopB in the absence of the repressor H-NS

LE Romero-González, D Pérez-Morales… - PLoS …, 2020 - journals.plos.org
Expression of virulence factors in non-typhoidal Salmonella enterica depends on a wide
variety of general and specific transcriptional factors that act in response to multiple …

Construction of Parkinson's disease marker-based weighted protein-protein interaction network for prioritization of co-expressed genes

G George, SV Parambath, SB Lokappa, J Varkey - Gene, 2019 - Elsevier
Background: Parkinson's disease (PD) is a complex neurodegenerative movement disorder
that primarily results due to the loss of dopaminergic neurons in the substantia nigra region …

A side-effect free method for identifying cancer drug targets

MI Ashraf, SK Ong, S Mujawar, S Pawar, P More… - Scientific reports, 2018 - nature.com
Identifying effective drug targets, with little or no side effects, remains an ever challenging
task. A potential pitfall of failing to uncover the correct drug targets, due to side effect of …